Assessment of breast cancer recurrence with contrast-enhanced subtraction MR imaging: Preliminary results in 26 patients

R. Gilles, J. M. Guinebretiere, L. G. Shapeero, A. Lesnik, G. Contesso, D. Sarrazin, J. Masselot, D. Vanel

Research output: Contribution to journalArticlepeer-review

Abstract

Local relapse was suspected in 26 women treated conservatively for breast cancer. All women underwent routine magnetic resonance (MR) imaging and a dynamic MR subtraction study after injection of gadolinium- tetraazacyclododecanetetraacetic acid. Twelve women had no local relapse. Surgical biopsy enabled confirmation of recurrence in 14 patients. Routine MR imaging did not allow differentiation of recurrence from glandular or scar tissue. Except for one case of fat necrosis, patients without local relapse showed no contrast enhancement 1 minute 34 seconds after injection. At dynamic MR imaging, all recurrences showed contrast enhancement 1 minute 34 seconds after injection. Nodular enhancement (n = 11) was found in invasive carcinoma, whereas linear enhancement was seen in intraductal carcinoma (n = 3). Subtraction of precontrast from postcontrast images always allowed better visualization of contrast enhancement. Contrast-enhanced subtraction dynamic MR imaging may prove to be accurate in diagnosis of local relapses of breast cancer.

Original languageEnglish
Pages (from-to)473-478
Number of pages6
JournalRadiology
Volume188
Issue number2
Publication statusPublished - 1993

Keywords

  • Breast neoplasms, diagnosis
  • Breast neoplasms, postoperative
  • Magnetic resonance (MR), contrast enhancement
  • Magnetic resonance (MR), pulse sequences

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

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