Assessment of QT-RR intervals relation in patients with atrial fibrillation

L. Iozzia; L. T. Mainardi; F. Lombardi; V. D A Corino

doi:10.1109/CIC.2015.7411037

Assessment of QT-RR intervals relation in patients with atrial fibrillation

L. Iozzia, L. T. Mainardi, F. Lombardi, V. D A Corino

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

QT-RR relation has been deeply investigated during sinus rhythm. However there are not established methods for the evaluation of QT-RR relation in patients with atrial fibrillation (AF). The aim of the present study was to assess the relation between QT and preceding RR intervals in ECG signal of patients with AF using different methods. We analysed data from 26 patients with persistent AF. A two-step procedure was used to detect T wave apex. In order to consider QT lag phenomenon during AF, the relation between RT and RR intervals was assessed by different methods, using from 1 to 5 preceding RR intervals. A linear regression was applied to compare the slopes. A slightly increase of the QT-RR slope was observed when a larger number of preceding RR intervals was considered (RT - RR₁ 0:030 ± 0:013, RT - RR_1-2 0:028 ± 0:012, n.s., RT - RR_1-3 0:033 ± 0:012, n.s., RT - RR_1-4 0:035 ± 0:016, p <0:0001, RT - RR_1-5 0:039 ± 0:018, p <0:0001, RT -RR_(1-5)m 0:048±0:022, p <0:0001, RT - RR₂ 0:000 ± 0:007, p <0:0001). The most significant variation was observed among the mean value of RT -RR₁ slope with the mean value of RT -RR_(1-5)m slope. Interestingly the RT-RR correlation was completely lost when only the second previous RR interval was considered.

Original language	English
Title of host publication	Computing in Cardiology
Publisher	IEEE Computer Society
Pages	821-824
Number of pages	4
Volume	42
ISBN (Print)	9781509006854
DOIs	https://doi.org/10.1109/CIC.2015.7411037
Publication status	Published - Feb 16 2016
Event	42nd Computing in Cardiology Conference, CinC 2015 - Nice, France Duration: Sep 6 2015 → Sep 9 2015

Other

Other	42nd Computing in Cardiology Conference, CinC 2015
Country/Territory	France
City	Nice
Period	9/6/15 → 9/9/15

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Computer Science(all)

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10.1109/CIC.2015.7411037

Cite this

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title = "Assessment of QT-RR intervals relation in patients with atrial fibrillation",

abstract = "QT-RR relation has been deeply investigated during sinus rhythm. However there are not established methods for the evaluation of QT-RR relation in patients with atrial fibrillation (AF). The aim of the present study was to assess the relation between QT and preceding RR intervals in ECG signal of patients with AF using different methods. We analysed data from 26 patients with persistent AF. A two-step procedure was used to detect T wave apex. In order to consider QT lag phenomenon during AF, the relation between RT and RR intervals was assessed by different methods, using from 1 to 5 preceding RR intervals. A linear regression was applied to compare the slopes. A slightly increase of the QT-RR slope was observed when a larger number of preceding RR intervals was considered (RT - RR1 0:030 ± 0:013, RT - RR1-2 0:028 ± 0:012, n.s., RT - RR1-3 0:033 ± 0:012, n.s., RT - RR1-4 0:035 ± 0:016, p <0:0001, RT - RR1-5 0:039 ± 0:018, p <0:0001, RT -RR(1-5)m 0:048±0:022, p <0:0001, RT - RR2 0:000 ± 0:007, p <0:0001). The most significant variation was observed among the mean value of RT -RR1 slope with the mean value of RT -RR(1-5)m slope. Interestingly the RT-RR correlation was completely lost when only the second previous RR interval was considered.",

author = "L. Iozzia and Mainardi, {L. T.} and F. Lombardi and Corino, {V. D A}",

year = "2016",

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T1 - Assessment of QT-RR intervals relation in patients with atrial fibrillation

AU - Iozzia, L.

AU - Mainardi, L. T.

AU - Lombardi, F.

AU - Corino, V. D A

PY - 2016/2/16

Y1 - 2016/2/16

N2 - QT-RR relation has been deeply investigated during sinus rhythm. However there are not established methods for the evaluation of QT-RR relation in patients with atrial fibrillation (AF). The aim of the present study was to assess the relation between QT and preceding RR intervals in ECG signal of patients with AF using different methods. We analysed data from 26 patients with persistent AF. A two-step procedure was used to detect T wave apex. In order to consider QT lag phenomenon during AF, the relation between RT and RR intervals was assessed by different methods, using from 1 to 5 preceding RR intervals. A linear regression was applied to compare the slopes. A slightly increase of the QT-RR slope was observed when a larger number of preceding RR intervals was considered (RT - RR1 0:030 ± 0:013, RT - RR1-2 0:028 ± 0:012, n.s., RT - RR1-3 0:033 ± 0:012, n.s., RT - RR1-4 0:035 ± 0:016, p <0:0001, RT - RR1-5 0:039 ± 0:018, p <0:0001, RT -RR(1-5)m 0:048±0:022, p <0:0001, RT - RR2 0:000 ± 0:007, p <0:0001). The most significant variation was observed among the mean value of RT -RR1 slope with the mean value of RT -RR(1-5)m slope. Interestingly the RT-RR correlation was completely lost when only the second previous RR interval was considered.

AB - QT-RR relation has been deeply investigated during sinus rhythm. However there are not established methods for the evaluation of QT-RR relation in patients with atrial fibrillation (AF). The aim of the present study was to assess the relation between QT and preceding RR intervals in ECG signal of patients with AF using different methods. We analysed data from 26 patients with persistent AF. A two-step procedure was used to detect T wave apex. In order to consider QT lag phenomenon during AF, the relation between RT and RR intervals was assessed by different methods, using from 1 to 5 preceding RR intervals. A linear regression was applied to compare the slopes. A slightly increase of the QT-RR slope was observed when a larger number of preceding RR intervals was considered (RT - RR1 0:030 ± 0:013, RT - RR1-2 0:028 ± 0:012, n.s., RT - RR1-3 0:033 ± 0:012, n.s., RT - RR1-4 0:035 ± 0:016, p <0:0001, RT - RR1-5 0:039 ± 0:018, p <0:0001, RT -RR(1-5)m 0:048±0:022, p <0:0001, RT - RR2 0:000 ± 0:007, p <0:0001). The most significant variation was observed among the mean value of RT -RR1 slope with the mean value of RT -RR(1-5)m slope. Interestingly the RT-RR correlation was completely lost when only the second previous RR interval was considered.

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T2 - 42nd Computing in Cardiology Conference, CinC 2015

Y2 - 6 September 2015 through 9 September 2015

ER -

Assessment of QT-RR intervals relation in patients with atrial fibrillation

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