TY - JOUR
T1 - Assessment of seasonal influenza vaccine effectiveness in patients from a central Italy reference hospital
T2 - Pitfalls and intricacies from a pilot case-control study
AU - Simona, Costanzo
AU - de Katleen, Gaetano Donati
AU - Lara, Campana
AU - Olivieri, Marco
AU - Rosaria, Santangelo
AU - Maurizio, Sanguinetti
AU - Roberto, Cauda
AU - Licia, Iacoviello
PY - 2014
Y1 - 2014
N2 - Background: Influenza vaccination protects high-risk populations from severe outcomes.Methods: During the 2011-2012 flu season at "Gemelli Hospital" in Rome, all hospitalised patients who developed suspected influenza-like illness within 14 days were recruited to assess the feasibility of testing the influenza vaccine effectiveness against laboratory-confirmed influenza requiring hospitalisation.Conclusions: No difference in vaccine status between patients with positive and negative laboratory tests was found due to the small sample size. Larger numbers are required to explore influenza vaccine effectiveness.Results: Sixty-two patients were recruited; among them, 18 were laboratory confirmed for influenza A or B. In the target group for vaccination (N=47), the prevalence of vaccinated subjects was less than expected (38%).
AB - Background: Influenza vaccination protects high-risk populations from severe outcomes.Methods: During the 2011-2012 flu season at "Gemelli Hospital" in Rome, all hospitalised patients who developed suspected influenza-like illness within 14 days were recruited to assess the feasibility of testing the influenza vaccine effectiveness against laboratory-confirmed influenza requiring hospitalisation.Conclusions: No difference in vaccine status between patients with positive and negative laboratory tests was found due to the small sample size. Larger numbers are required to explore influenza vaccine effectiveness.Results: Sixty-two patients were recruited; among them, 18 were laboratory confirmed for influenza A or B. In the target group for vaccination (N=47), the prevalence of vaccinated subjects was less than expected (38%).
KW - Hospitalisation
KW - Influenza vaccine effectiveness
KW - Influenza-like illness
KW - Pilot case-control study
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U2 - 10.2427/9157
DO - 10.2427/9157
M3 - Article
AN - SCOPUS:84907462189
VL - 11
SP - e9157-1-e9157-6
JO - Epidemiology Biostatistics and Public Health
JF - Epidemiology Biostatistics and Public Health
SN - 2282-2305
IS - 3
ER -