Assessment of sympathetic baroreflex control during orthostatic challenge before and after prolonged head-down bed rest

Andrea Marchi, Tito Bassani, Vlasta Bari, Karsten Heusser, Jens Tank, Jens Jordan, Franca Barbic, Raffaello Furlan, Alberto Porta

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The study characterizes the sympathetic baroreflex control through the assessment of sympathetic baroreflex sensitivity (sBRS). sBRS was assessed as the slope of the regression line of the conditional probability of detecting a burst on the integrated muscle nerve sympathetic activity given an assigned diastolic arterial pressure (DAP) on DAP. sBRS was assessed during orthostatic challenge before and after 21 days -6 degrees head-down bed rest (HDBR) confinement. We identified an effect of the prolonged HDBR and an impairment of the sympathetic baroreflex just before pre-syncope symptoms induced by the orthostatic challenge, thus suggesting a possible role of the sympathetic baroreflex in the origin of neurally-mediated syncope.

Original languageEnglish
Title of host publication2014 8th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2014
PublisherIEEE Computer Society
Pages39-40
Number of pages2
ISBN (Print)9781479939695
DOIs
Publication statusPublished - 2014
Event2014 8th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2014 - Trento, Italy
Duration: May 25 2014May 28 2014

Other

Other2014 8th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2014
CountryItaly
CityTrento
Period5/25/145/28/14

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ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Marchi, A., Bassani, T., Bari, V., Heusser, K., Tank, J., Jordan, J., Barbic, F., Furlan, R., & Porta, A. (2014). Assessment of sympathetic baroreflex control during orthostatic challenge before and after prolonged head-down bed rest. In 2014 8th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2014 (pp. 39-40). [6847508] IEEE Computer Society. https://doi.org/10.1109/ESGCO.2014.6847508