Abstract
In Italy, the "silent-consent" principle of donor's willingness regulates organ donation for postmortem transplantation, but civil incompetence excludes it. We investigated decisional capacity for organ donation for transplantation of 30 controls and 30 nonincompetent patients with schizophrenia as related to clinical symptoms, cognition, and functioning. Assessments were carried out through the Competence for Donation Assessment Scale (CDAS), Brief Psychiatric Rating Scale (BPRS), Scale for the Assessment of Positive Symptoms (SAPS), Scale for the Assessment of Negative Symptoms, Life Skills Profile (LSP), Raven's Colored Progressive Matrices (RCPM), Wisconsin Card Sorting Test, Rey RI, Rey RD, and Visual Search. Patients and controls differed on the CDAS Understanding and Choice Expression areas. Patients showed significant inverse bivariate correlations between CDAS Understanding and scores on total BPRS, LSP self-care scale, and RCPM cognitive test. Our results show that decisional capacity for participating in research does not predict decisional capacity for postmortem organ donation in patients with schizophrenic or schizoaffective psychosis; hence, before judging consent for donation, patients must be provided with enhanced information to better understand this delicate issue.
| Original language | English |
|---|---|
| Pages (from-to) | 669-676 |
| Number of pages | 8 |
| Journal | Journal of Forensic Sciences |
| Volume | 55 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - May 2010 |
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Keywords
- Ethics
- Forensic science
- Informed consent
- MacArthur Competence Assessment Tool for Treatment
- Organ donation
- Schizophrenia
- Transplantation
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Genetics
- Medicine(all)
Cite this
Assessment of the capacity to express informed consent for organ donation in patients with schizophrenia. / De Marco, Maria Civita; Sani, Gabriele; Manfredi, Giovanni; Pacchiarotti, Isabella; Savoja, Valeria; Balbi, Andrea; Mazzarini, Lorenzo; Borriello, Adriana; Kotzalidis, Giorgio D.; Tatarelli, Roberto; Girardi, Paolo; Ferracuti, Stefano.
In: Journal of Forensic Sciences, Vol. 55, No. 3, 05.2010, p. 669-676.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Assessment of the capacity to express informed consent for organ donation in patients with schizophrenia
AU - De Marco, Maria Civita
AU - Sani, Gabriele
AU - Manfredi, Giovanni
AU - Pacchiarotti, Isabella
AU - Savoja, Valeria
AU - Balbi, Andrea
AU - Mazzarini, Lorenzo
AU - Borriello, Adriana
AU - Kotzalidis, Giorgio D.
AU - Tatarelli, Roberto
AU - Girardi, Paolo
AU - Ferracuti, Stefano
PY - 2010/5
Y1 - 2010/5
N2 - In Italy, the "silent-consent" principle of donor's willingness regulates organ donation for postmortem transplantation, but civil incompetence excludes it. We investigated decisional capacity for organ donation for transplantation of 30 controls and 30 nonincompetent patients with schizophrenia as related to clinical symptoms, cognition, and functioning. Assessments were carried out through the Competence for Donation Assessment Scale (CDAS), Brief Psychiatric Rating Scale (BPRS), Scale for the Assessment of Positive Symptoms (SAPS), Scale for the Assessment of Negative Symptoms, Life Skills Profile (LSP), Raven's Colored Progressive Matrices (RCPM), Wisconsin Card Sorting Test, Rey RI, Rey RD, and Visual Search. Patients and controls differed on the CDAS Understanding and Choice Expression areas. Patients showed significant inverse bivariate correlations between CDAS Understanding and scores on total BPRS, LSP self-care scale, and RCPM cognitive test. Our results show that decisional capacity for participating in research does not predict decisional capacity for postmortem organ donation in patients with schizophrenic or schizoaffective psychosis; hence, before judging consent for donation, patients must be provided with enhanced information to better understand this delicate issue.
AB - In Italy, the "silent-consent" principle of donor's willingness regulates organ donation for postmortem transplantation, but civil incompetence excludes it. We investigated decisional capacity for organ donation for transplantation of 30 controls and 30 nonincompetent patients with schizophrenia as related to clinical symptoms, cognition, and functioning. Assessments were carried out through the Competence for Donation Assessment Scale (CDAS), Brief Psychiatric Rating Scale (BPRS), Scale for the Assessment of Positive Symptoms (SAPS), Scale for the Assessment of Negative Symptoms, Life Skills Profile (LSP), Raven's Colored Progressive Matrices (RCPM), Wisconsin Card Sorting Test, Rey RI, Rey RD, and Visual Search. Patients and controls differed on the CDAS Understanding and Choice Expression areas. Patients showed significant inverse bivariate correlations between CDAS Understanding and scores on total BPRS, LSP self-care scale, and RCPM cognitive test. Our results show that decisional capacity for participating in research does not predict decisional capacity for postmortem organ donation in patients with schizophrenic or schizoaffective psychosis; hence, before judging consent for donation, patients must be provided with enhanced information to better understand this delicate issue.
KW - Ethics
KW - Forensic science
KW - Informed consent
KW - MacArthur Competence Assessment Tool for Treatment
KW - Organ donation
KW - Schizophrenia
KW - Transplantation
UR - http://www.scopus.com/inward/record.url?scp=77951140963&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951140963&partnerID=8YFLogxK
U2 - 10.1111/j.1556-4029.2010.01364.x
DO - 10.1111/j.1556-4029.2010.01364.x
M3 - Article
C2 - 20345780
AN - SCOPUS:77951140963
VL - 55
SP - 669
EP - 676
JO - Journal of Forensic Sciences
JF - Journal of Forensic Sciences
SN - 0022-1198
IS - 3
ER -