Assessment of the hypnotic/sedative effects and toxicity of Passiflora edulis aqueous extract in rodents and humans

E. Maluf, H. M T Baros, M. L. Frochtengarten, R. Benti, J. R. Leite

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Passiflora species are used in folk medicine as hypnotic and sedative treatments. In this study the hypnotic-sedative effects and toxicity of Passiflora edulis were assessed in rats and mice and in healthy volunteers. It was verified that some samples of Pasiflora edulis had a nonspecific central nervous system depressant effect. Furthermore, hepatobiliary and pancreatic toxicity to animals and humans were detected.

Original languageEnglish
Pages (from-to)262-266
Number of pages5
JournalPhytotherapy Research
Volume5
Issue number6
Publication statusPublished - 1991

Fingerprint

Passiflora
Hypnotics and Sedatives
Toxicity
Rodentia
Central Nervous System Depressants
Medicine
Rats
Animals
Traditional Medicine
Healthy Volunteers

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

Cite this

Assessment of the hypnotic/sedative effects and toxicity of Passiflora edulis aqueous extract in rodents and humans. / Maluf, E.; Baros, H. M T; Frochtengarten, M. L.; Benti, R.; Leite, J. R.

In: Phytotherapy Research, Vol. 5, No. 6, 1991, p. 262-266.

Research output: Contribution to journalArticle

Maluf, E. ; Baros, H. M T ; Frochtengarten, M. L. ; Benti, R. ; Leite, J. R. / Assessment of the hypnotic/sedative effects and toxicity of Passiflora edulis aqueous extract in rodents and humans. In: Phytotherapy Research. 1991 ; Vol. 5, No. 6. pp. 262-266.
@article{caa524840042486ea6d15f8d1e83ca3d,
title = "Assessment of the hypnotic/sedative effects and toxicity of Passiflora edulis aqueous extract in rodents and humans",
abstract = "Passiflora species are used in folk medicine as hypnotic and sedative treatments. In this study the hypnotic-sedative effects and toxicity of Passiflora edulis were assessed in rats and mice and in healthy volunteers. It was verified that some samples of Pasiflora edulis had a nonspecific central nervous system depressant effect. Furthermore, hepatobiliary and pancreatic toxicity to animals and humans were detected.",
author = "E. Maluf and Baros, {H. M T} and Frochtengarten, {M. L.} and R. Benti and Leite, {J. R.}",
year = "1991",
language = "English",
volume = "5",
pages = "262--266",
journal = "Phytotherapy Research",
issn = "0951-418X",
publisher = "John Wiley and Sons Ltd",
number = "6",

}

TY - JOUR

T1 - Assessment of the hypnotic/sedative effects and toxicity of Passiflora edulis aqueous extract in rodents and humans

AU - Maluf, E.

AU - Baros, H. M T

AU - Frochtengarten, M. L.

AU - Benti, R.

AU - Leite, J. R.

PY - 1991

Y1 - 1991

N2 - Passiflora species are used in folk medicine as hypnotic and sedative treatments. In this study the hypnotic-sedative effects and toxicity of Passiflora edulis were assessed in rats and mice and in healthy volunteers. It was verified that some samples of Pasiflora edulis had a nonspecific central nervous system depressant effect. Furthermore, hepatobiliary and pancreatic toxicity to animals and humans were detected.

AB - Passiflora species are used in folk medicine as hypnotic and sedative treatments. In this study the hypnotic-sedative effects and toxicity of Passiflora edulis were assessed in rats and mice and in healthy volunteers. It was verified that some samples of Pasiflora edulis had a nonspecific central nervous system depressant effect. Furthermore, hepatobiliary and pancreatic toxicity to animals and humans were detected.

UR - http://www.scopus.com/inward/record.url?scp=0025990666&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025990666&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0025990666

VL - 5

SP - 262

EP - 266

JO - Phytotherapy Research

JF - Phytotherapy Research

SN - 0951-418X

IS - 6

ER -