Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1

B. Scognamiglio, G. Baldassarre, C. Cassano, M. Tucci, N. Montuori, R. Dono, G. Lembo, A. Barra, C. T. Lago, G. Viglietto, M. Rocchi, M. Graziella Persico

Research output: Contribution to journalArticle

Abstract

The human teratocarcinoma derived growth factor 1 (TDGF1) gene maps on chromosome (Chr) 3p21.3. One pseudogene (TDGF3) maps on Chr Xq21→q22. We now report the nucleotide sequence and chromosome location of three additional TDGF pseudogenes. The three new sequences (TDGF2, TDGF4 and TDGF5) are truncated at the 5' end and have accumulated several point mutations, deletions and insertions. TDGF2, TDGF4 and TDGF6 map on Chrs 2q37, 6p25 and 3q22, respectively. Finally, Southern blot analysis of DNA from normal individuals shows a highly variable restriction pattern of the TDGF sequences.

Original languageEnglish
Pages (from-to)220-224
Number of pages5
JournalCytogenetics and Cell Genetics
Volume84
Issue number3-4
Publication statusPublished - 1999

Fingerprint

Teratocarcinoma
Intercellular Signaling Peptides and Proteins
Pseudogenes
Chromosomes
Southern Blotting
Point Mutation
DNA
Genes

ASJC Scopus subject areas

  • Genetics
  • Cell Biology

Cite this

Scognamiglio, B., Baldassarre, G., Cassano, C., Tucci, M., Montuori, N., Dono, R., ... Persico, M. G. (1999). Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1. Cytogenetics and Cell Genetics, 84(3-4), 220-224.

Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1. / Scognamiglio, B.; Baldassarre, G.; Cassano, C.; Tucci, M.; Montuori, N.; Dono, R.; Lembo, G.; Barra, A.; Lago, C. T.; Viglietto, G.; Rocchi, M.; Persico, M. Graziella.

In: Cytogenetics and Cell Genetics, Vol. 84, No. 3-4, 1999, p. 220-224.

Research output: Contribution to journalArticle

Scognamiglio, B, Baldassarre, G, Cassano, C, Tucci, M, Montuori, N, Dono, R, Lembo, G, Barra, A, Lago, CT, Viglietto, G, Rocchi, M & Persico, MG 1999, 'Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1', Cytogenetics and Cell Genetics, vol. 84, no. 3-4, pp. 220-224.
Scognamiglio, B. ; Baldassarre, G. ; Cassano, C. ; Tucci, M. ; Montuori, N. ; Dono, R. ; Lembo, G. ; Barra, A. ; Lago, C. T. ; Viglietto, G. ; Rocchi, M. ; Persico, M. Graziella. / Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1. In: Cytogenetics and Cell Genetics. 1999 ; Vol. 84, No. 3-4. pp. 220-224.
@article{2c035b2e9bcb4d7593ccf3da4e3231e7,
title = "Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1",
abstract = "The human teratocarcinoma derived growth factor 1 (TDGF1) gene maps on chromosome (Chr) 3p21.3. One pseudogene (TDGF3) maps on Chr Xq21→q22. We now report the nucleotide sequence and chromosome location of three additional TDGF pseudogenes. The three new sequences (TDGF2, TDGF4 and TDGF5) are truncated at the 5' end and have accumulated several point mutations, deletions and insertions. TDGF2, TDGF4 and TDGF6 map on Chrs 2q37, 6p25 and 3q22, respectively. Finally, Southern blot analysis of DNA from normal individuals shows a highly variable restriction pattern of the TDGF sequences.",
author = "B. Scognamiglio and G. Baldassarre and C. Cassano and M. Tucci and N. Montuori and R. Dono and G. Lembo and A. Barra and Lago, {C. T.} and G. Viglietto and M. Rocchi and Persico, {M. Graziella}",
year = "1999",
language = "English",
volume = "84",
pages = "220--224",
journal = "Cytogenetics and Cell Genetics",
issn = "0301-0171",
publisher = "S. Karger AG",
number = "3-4",

}

TY - JOUR

T1 - Assignment of human teratocarcinoma derived growth factor (TDGF) sequences to chromosomes 2q37, 3q22, 6p25 and 19q13.1

AU - Scognamiglio, B.

AU - Baldassarre, G.

AU - Cassano, C.

AU - Tucci, M.

AU - Montuori, N.

AU - Dono, R.

AU - Lembo, G.

AU - Barra, A.

AU - Lago, C. T.

AU - Viglietto, G.

AU - Rocchi, M.

AU - Persico, M. Graziella

PY - 1999

Y1 - 1999

N2 - The human teratocarcinoma derived growth factor 1 (TDGF1) gene maps on chromosome (Chr) 3p21.3. One pseudogene (TDGF3) maps on Chr Xq21→q22. We now report the nucleotide sequence and chromosome location of three additional TDGF pseudogenes. The three new sequences (TDGF2, TDGF4 and TDGF5) are truncated at the 5' end and have accumulated several point mutations, deletions and insertions. TDGF2, TDGF4 and TDGF6 map on Chrs 2q37, 6p25 and 3q22, respectively. Finally, Southern blot analysis of DNA from normal individuals shows a highly variable restriction pattern of the TDGF sequences.

AB - The human teratocarcinoma derived growth factor 1 (TDGF1) gene maps on chromosome (Chr) 3p21.3. One pseudogene (TDGF3) maps on Chr Xq21→q22. We now report the nucleotide sequence and chromosome location of three additional TDGF pseudogenes. The three new sequences (TDGF2, TDGF4 and TDGF5) are truncated at the 5' end and have accumulated several point mutations, deletions and insertions. TDGF2, TDGF4 and TDGF6 map on Chrs 2q37, 6p25 and 3q22, respectively. Finally, Southern blot analysis of DNA from normal individuals shows a highly variable restriction pattern of the TDGF sequences.

UR - http://www.scopus.com/inward/record.url?scp=0033019351&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033019351&partnerID=8YFLogxK

M3 - Article

C2 - 10393436

AN - SCOPUS:0033019351

VL - 84

SP - 220

EP - 224

JO - Cytogenetics and Cell Genetics

JF - Cytogenetics and Cell Genetics

SN - 0301-0171

IS - 3-4

ER -