Assisted reproductive technology treatments and quality of life: a longitudinal study among subfertile women and men

Francesca Agostini, Fiorella Monti, Federica Andrei, Marcella Paterlini, Stefano Palomba, Giovanni Battista la Sala

Research output: Research - peer-reviewArticle

Abstract

Purpose: Quality of life (QoL) may represent a comprehensive indicator for the assessment of the psychological impact of complex clinical conditions, such as infertility. Infertile women have a worse QoL compared to both infertile men and non-infertile controls. However, the initial phases of infertility treatments have been frequently investigated using cross-sectional study designs. This prospective longitudinal study aimed at assessing the health-related QoL change across different phases of assisted reproductive technology (ART) treatments in subfertile women and men. Methods: Eighty-five subfertile women and men undergoing ART cycles were assessed at the beginning of the ovarian stimulation, during oocyte retrieval before discharging, and around 14 days after the embryo transfer. QoL was assessed through the Short Form 36. Results: Irrespective of the cause of infertility, work status, and age, QoL levels decreased from the first to the third assessment, and women scored significantly lower than men to each QoL indicator. Additionally, a higher number of previous ART failures had a negative impact on QoL, irrespective of gender and the phase of treatment. ART outcome marginally affected women’s QoL across time. Conclusion: Infertile women have a worse QoL throughout all phases of ARTs compared to men, and this difference increases in infertile patients with more than one previous ART failure.

LanguageEnglish
Pages1-9
Number of pages9
JournalJournal of Assisted Reproduction and Genetics
DOIs
StateAccepted/In press - Jul 21 2017

Fingerprint

Assisted Reproductive Techniques
Longitudinal Studies
Quality of Life
Therapeutics
Infertility
Oocyte Retrieval
Ovulation Induction
Embryo Transfer
Cross-Sectional Studies
Prospective Studies
Psychology

Keywords

  • Assisted reproductive technology
  • Infertility
  • Longitudinal study
  • Men
  • Quality of life
  • Women

ASJC Scopus subject areas

  • Reproductive Medicine
  • Genetics
  • Obstetrics and Gynaecology
  • Developmental Biology
  • Genetics(clinical)

Cite this

Assisted reproductive technology treatments and quality of life : a longitudinal study among subfertile women and men. / Agostini, Francesca; Monti, Fiorella; Andrei, Federica; Paterlini, Marcella; Palomba, Stefano; la Sala, Giovanni Battista.

In: Journal of Assisted Reproduction and Genetics, 21.07.2017, p. 1-9.

Research output: Research - peer-reviewArticle

Agostini, Francesca ; Monti, Fiorella ; Andrei, Federica ; Paterlini, Marcella ; Palomba, Stefano ; la Sala, Giovanni Battista. / Assisted reproductive technology treatments and quality of life : a longitudinal study among subfertile women and men. In: Journal of Assisted Reproduction and Genetics. 2017 ; pp. 1-9
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