Association between aerobic fitness and indices of autonomic regulation: Cardiovascular risk implications

Roberto Sala; Mara Malacarne; Massimo Pagani; Daniela Lucini

Association between aerobic fitness and indices of autonomic regulation: Cardiovascular risk implications

Roberto Sala, Mara Malacarne, Massimo Pagani, Daniela Lucini

Istituto Clinico Humanitas

Research output: Contribution to journal › Article › peer-review

Abstract

BACKGROUND: In the general population higher levels of exercise capacity seem to protect the cardiovascular system with effects well beyond traditional risk factors. We hypothesize that this phenomenon, called "risk factor gap", could be ascribed to functional components, such as autonomic adaptation to aerobic training. METHODS: In 257 subjects (age 36.2±0.8 years) we measured VO₂peak (incremental cycling exercise), together with arterial pressure and autonomic proxies (baroreflex gain, R-R variance and standing induced increase in marker of excitatory oscillatory regulation of the SA node, ALF_RRnu). RESULTS: Autonomic proxies appeared significantly correlated with indicators of aerobic fitness (age and gender corrected correlation between VO₂peak, baroreflex gain: 7=0.277, P2peak (poor, medium and good). Autonomic indices and arterial pressure appeared significantly ordered with categories of VO₂peak (P

Original language	English
Pages (from-to)	794-801
Number of pages	8
Journal	Journal of Sports Medicine and Physical Fitness
Volume	56
Issue number	6
Publication status	Published - Jun 1 2016

Keywords

Autonomic nervous system
Baroreflex
Heart rate
Physical exercise
Prevention

ASJC Scopus subject areas

Orthopedics and Sports Medicine
Physical Therapy, Sports Therapy and Rehabilitation

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AU - Sala, Roberto

AU - Malacarne, Mara

AU - Pagani, Massimo

AU - Lucini, Daniela

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Y1 - 2016/6/1

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AB - BACKGROUND: In the general population higher levels of exercise capacity seem to protect the cardiovascular system with effects well beyond traditional risk factors. We hypothesize that this phenomenon, called "risk factor gap", could be ascribed to functional components, such as autonomic adaptation to aerobic training. METHODS: In 257 subjects (age 36.2±0.8 years) we measured VO2peak (incremental cycling exercise), together with arterial pressure and autonomic proxies (baroreflex gain, R-R variance and standing induced increase in marker of excitatory oscillatory regulation of the SA node, ALFRRnu). RESULTS: Autonomic proxies appeared significantly correlated with indicators of aerobic fitness (age and gender corrected correlation between VO2peak, baroreflex gain: 7=0.277, P2peak (poor, medium and good). Autonomic indices and arterial pressure appeared significantly ordered with categories of VO2peak (P

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Association between aerobic fitness and indices of autonomic regulation: Cardiovascular risk implications

Abstract

Keywords

ASJC Scopus subject areas

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