Abstract
Physical activity (PA) and micronutrients such as calcium (Ca), vitamin D (25OHD), and phosphate (PO) are important determinants of skeletal development. This case-control study examined the association of these nutritional biomarkers and different PA behaviours, such as habitual PA, weight-bearing exercise (WBE) and sedentary time (SED) with bone stiffness (SI) in 1819 2-9-year-old children from the IDEFICS study (2007-2008). SI was measured on the calcaneus using quantitative ultrasound. Serum and urine Ca and PO and serum 25OHD were determined. Children's sports activities were reported by parents using a standardised questionnaire. A subsample of 1089 children had accelerometer-based PA data (counts per minute, cpm). Moderate-to-vigorous PA (MVPA) and SED were estimated. Children with poor SI (below the 15th age-/sex-/height-specific percentile) were defined as cases (N. =. 603). Randomly selected controls (N. =. 1216) were matched by age, sex, and country. Odds ratios (OR) for poor SI were calculated by conditional logistic regression for all biomarkers and PA behaviour variables separately and combined (expressed as tertiles and dichotomised variables, respectively). ORs were adjusted for fat-free mass, dairy product consumption, and daylight duration. We observed increased ORs for no sports (OR. =. 1.39, p.
| Original language | English |
|---|---|
| Pages (from-to) | 142-149 |
| Number of pages | 8 |
| Journal | Bone |
| Volume | 78 |
| DOIs | |
| Publication status | Published - Sep 1 2015 |
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Keywords
- Bone health
- Bone stiffness
- Case-control study
- Epidemiology
- Quantitative ultrasound
- Weight-bearing exercise
ASJC Scopus subject areas
- Physiology
- Endocrinology, Diabetes and Metabolism
- Histology
Cite this
Association between bone stiffness and nutritional biomarkers combined with weight-bearing exercise, physical activity, and sedentary time in preadolescent children. A case-control study. / Herrmann, Diana; Pohlabeln, Hermann; Gianfagna, Francesco; Konstabel, Kenn; Lissner, Lauren; Mårild, Staffan; Molnar, Dénes; Moreno, Luis A.; Siani, Alfonso; Sioen, Isabelle; Veidebaum, Toomas; Ahrens, Wolfgang.
In: Bone, Vol. 78, 01.09.2015, p. 142-149.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Association between bone stiffness and nutritional biomarkers combined with weight-bearing exercise, physical activity, and sedentary time in preadolescent children. A case-control study
AU - Herrmann, Diana
AU - Pohlabeln, Hermann
AU - Gianfagna, Francesco
AU - Konstabel, Kenn
AU - Lissner, Lauren
AU - Mårild, Staffan
AU - Molnar, Dénes
AU - Moreno, Luis A.
AU - Siani, Alfonso
AU - Sioen, Isabelle
AU - Veidebaum, Toomas
AU - Ahrens, Wolfgang
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Physical activity (PA) and micronutrients such as calcium (Ca), vitamin D (25OHD), and phosphate (PO) are important determinants of skeletal development. This case-control study examined the association of these nutritional biomarkers and different PA behaviours, such as habitual PA, weight-bearing exercise (WBE) and sedentary time (SED) with bone stiffness (SI) in 1819 2-9-year-old children from the IDEFICS study (2007-2008). SI was measured on the calcaneus using quantitative ultrasound. Serum and urine Ca and PO and serum 25OHD were determined. Children's sports activities were reported by parents using a standardised questionnaire. A subsample of 1089 children had accelerometer-based PA data (counts per minute, cpm). Moderate-to-vigorous PA (MVPA) and SED were estimated. Children with poor SI (below the 15th age-/sex-/height-specific percentile) were defined as cases (N. =. 603). Randomly selected controls (N. =. 1216) were matched by age, sex, and country. Odds ratios (OR) for poor SI were calculated by conditional logistic regression for all biomarkers and PA behaviour variables separately and combined (expressed as tertiles and dichotomised variables, respectively). ORs were adjusted for fat-free mass, dairy product consumption, and daylight duration. We observed increased ORs for no sports (OR. =. 1.39, p.
AB - Physical activity (PA) and micronutrients such as calcium (Ca), vitamin D (25OHD), and phosphate (PO) are important determinants of skeletal development. This case-control study examined the association of these nutritional biomarkers and different PA behaviours, such as habitual PA, weight-bearing exercise (WBE) and sedentary time (SED) with bone stiffness (SI) in 1819 2-9-year-old children from the IDEFICS study (2007-2008). SI was measured on the calcaneus using quantitative ultrasound. Serum and urine Ca and PO and serum 25OHD were determined. Children's sports activities were reported by parents using a standardised questionnaire. A subsample of 1089 children had accelerometer-based PA data (counts per minute, cpm). Moderate-to-vigorous PA (MVPA) and SED were estimated. Children with poor SI (below the 15th age-/sex-/height-specific percentile) were defined as cases (N. =. 603). Randomly selected controls (N. =. 1216) were matched by age, sex, and country. Odds ratios (OR) for poor SI were calculated by conditional logistic regression for all biomarkers and PA behaviour variables separately and combined (expressed as tertiles and dichotomised variables, respectively). ORs were adjusted for fat-free mass, dairy product consumption, and daylight duration. We observed increased ORs for no sports (OR. =. 1.39, p.
KW - Bone health
KW - Bone stiffness
KW - Case-control study
KW - Epidemiology
KW - Quantitative ultrasound
KW - Weight-bearing exercise
UR - http://www.scopus.com/inward/record.url?scp=84929304343&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929304343&partnerID=8YFLogxK
U2 - 10.1016/j.bone.2015.04.043
DO - 10.1016/j.bone.2015.04.043
M3 - Article
C2 - 25952968
AN - SCOPUS:84929304343
VL - 78
SP - 142
EP - 149
JO - Bone
JF - Bone
SN - 8756-3282
ER -