Association between centriole and nuclear matrix in human lymphocytes

N. M. Maraldi, F. Marinelli, S. Amati, L. Cocco, P. Santi, S. Papa, A. Galanzi, E. Caramelli, A. Antonucci, G. Mazzotti

Research output: Chapter in Book/Report/Conference proceedingChapter


Nuclear matrices, purified from normal and chronic lymphocytic leukemia lymphocytes, exhibit a close association with the centriole. This finding suggests that the nuclear and cytoplasmic skeletal systems are linked by transmembrane connections represented by nuclear matrix constituents. This could account for the observed synchrony between transformations of the centriole and particular nuclear events which take place during the cell cycle and suggests that the nuclear matrix, besides being involved in DNA replication and chromosome condensation, should affect the centriole cycle which controls the cytoskeleton organization.

Original languageEnglish
Title of host publicationJournal of Submicroscopic Cytology
Number of pages6
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Anatomy
  • Histology


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