Association between dietary inflammatory index and prostate cancer among Italian men

Nitin Shivappa, Cristina Bosetti, Antonella Zucchetto, Maurizio Montella, Diego Serraino, Carlo La Vecchia, James R. Hébert

Research output: Contribution to journalArticlepeer-review


Previous studies have shown that various dietary components may be implicated in the aetiology of prostate cancer, although the results remain equivocal. The possible relationship of inflammation derived from dietary exposures with prostate cancer risk has not been investigated. We examined the ability of a newly developed dietary inflammatory index (DII) to predict prostate cancer risk in a case-control study conducted in Italy between 1991 and 2002. A total of 1294 patients aged Quartile 3 v. 1 1.32, 95% CI 1.03, 1.69 and ORQuartile 4 v. 1 1.33, 95% CI 1.01, 1.76; Ptrend = 0.04). These data suggest that a pro-inflammatory diet, as indicated by the increasing DII score, is a risk factor of prostate cancer in Italian men.

Original languageEnglish
Pages (from-to)278-283
Number of pages6
JournalBritish Journal of Nutrition
Issue number2
Publication statusPublished - Jan 28 2015


  • Case-control studies
  • Diet
  • Dietary inflammatory index
  • Inflammation
  • Italy
  • Prostate cancer

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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