Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis

H. F. Gu, P. Almgren, E. Lindholm, L. Frittitta, A. Pizzuti, V. Trischitta, L. C. Groop

Research output: Contribution to journalArticle

Abstract

We studied whether there is an association between the single nuceotide polymorphism c.533A>C (K121Q) in the glycoprotein PC-1 gene and features of the metabolic syndrome in case-control and intrafamily association studies in 922 subjects from Finland and Sweden. No difference was observed in the Q allele frequency between control subjects and type 2 diabetic subjects (12.9 vs. 15.1%). The QK genotype was associated with higher fasting plasma glucose (FPG) concentrations than the KK genotype in type 2 diabetic patients (P

Original languageEnglish
Pages (from-to)1601-1603
Number of pages3
JournalDiabetes
Volume49
Issue number9
Publication statusPublished - 2000

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Siblings
Genotype
Insulin
Glucose
Finland
Sweden
Gene Frequency
Genes
Fasting
ectonucleotide pyrophosphatase phosphodiesterase 1

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Gu, H. F., Almgren, P., Lindholm, E., Frittitta, L., Pizzuti, A., Trischitta, V., & Groop, L. C. (2000). Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis. Diabetes, 49(9), 1601-1603.

Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis. / Gu, H. F.; Almgren, P.; Lindholm, E.; Frittitta, L.; Pizzuti, A.; Trischitta, V.; Groop, L. C.

In: Diabetes, Vol. 49, No. 9, 2000, p. 1601-1603.

Research output: Contribution to journalArticle

Gu, HF, Almgren, P, Lindholm, E, Frittitta, L, Pizzuti, A, Trischitta, V & Groop, LC 2000, 'Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis', Diabetes, vol. 49, no. 9, pp. 1601-1603.
Gu, H. F. ; Almgren, P. ; Lindholm, E. ; Frittitta, L. ; Pizzuti, A. ; Trischitta, V. ; Groop, L. C. / Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis. In: Diabetes. 2000 ; Vol. 49, No. 9. pp. 1601-1603.
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