TY - JOUR
T1 - Association between venous and arterial thrombosis
T2 - Clinical implications
AU - Franchini, Massimo
AU - Mannucci, Pier Mannuccio
PY - 2012/6
Y1 - 2012/6
N2 - Venous and arterial thromboses have traditionally been regarded as separate diseases with different causes. However, recent epidemiological studies have documented an association between these vascular complications, probably due to the presence of more overlapping risk factors than previously recognized. This narrative review first focuses on the risk factors associated with both arterial and venous thrombotic events. In addition, it summarizes the more recent data on the risk of incident venous thromboembolism in patients with asymptomatic atherosclerosis or clinical manifestations of atherothrombosis, as well as on the risk of incident atherothrombotic events in patients with previous manifestation of venous thromboembolism. The potential clinical implications are also discussed.
AB - Venous and arterial thromboses have traditionally been regarded as separate diseases with different causes. However, recent epidemiological studies have documented an association between these vascular complications, probably due to the presence of more overlapping risk factors than previously recognized. This narrative review first focuses on the risk factors associated with both arterial and venous thrombotic events. In addition, it summarizes the more recent data on the risk of incident venous thromboembolism in patients with asymptomatic atherosclerosis or clinical manifestations of atherothrombosis, as well as on the risk of incident atherothrombotic events in patients with previous manifestation of venous thromboembolism. The potential clinical implications are also discussed.
KW - Arterial thrombosis
KW - Risk factors
KW - Therapy
KW - Venous thrombosis
UR - http://www.scopus.com/inward/record.url?scp=84860533004&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84860533004&partnerID=8YFLogxK
U2 - 10.1016/j.ejim.2012.02.008
DO - 10.1016/j.ejim.2012.02.008
M3 - Article
C2 - 22560380
AN - SCOPUS:84860533004
VL - 23
SP - 333
EP - 337
JO - European Journal of Internal Medicine
JF - European Journal of Internal Medicine
SN - 0953-6205
IS - 4
ER -