Association of celiac disease in patients with multiple sclerosis in Tuscany

Barbara Piccini, Monica Ulivelli, Maria Pia Amato, Sabina Bartalini, Mario Falcini, Marta Giannini, Eliana Magnani, Luca Massacesi, Anna Maria Repice, Marina Vascotto, Salvatore Grosso

Research output: Contribution to journalArticlepeer-review


Background and study purpose: To describe the comorbidity of celiac disease among a large cohort of multiple sclerosis patients in Tuscany. Methods: The association of celiac disease among multiple sclerosis adult patients (n=2050) was retrospectively evaluated. Results: 13 patients were diagnosed with celiac disease, the female:male ratio was 3.3:1 and the median age at diagnosis was 34.2 years (SD 13). Seventy-seven per cent of subjects complained about gastrointestinal symptoms. IgA anti- transglutaminase was positive in 85 % of cases and there was 70 % of villous atrophy. Conclusions: The frequency of celiac disease among multiple sclerosis patients examined was lower than in the general population (0.6 % vs 1 %) (p = 0.65).

Original languageEnglish
Pages (from-to)474-476
Number of pages3
JournalRevista Espanola de Enfermedades Digestivas
Issue number6
Publication statusPublished - Jun 1 2020


  • Celiac disease
  • Comorbidity.
  • Epidemiology
  • Multiple sclerosis

ASJC Scopus subject areas

  • Gastroenterology


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