Association of estrogen receptor-α gene polymorphisms with venous thrombosis

Federico Lussana; Elena M. Faioni; Carmelo Mavilia; Paolo Bucciarelli; Maria Luisa Brandi; Marco Cattaneo

Association of estrogen receptor-α gene polymorphisms with venous thrombosis

Federico Lussana, Elena M. Faioni, Carmelo Mavilia, Paolo Bucciarelli, Maria Luisa Brandi, Marco Cattaneo

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

XbaI and PvuII polymorphisms of the estrogen receptor-α gene (ERα) have been associated with several multifactorial diseases. We studied the distribution of ERα polymorphisms in patients with deep vein thrombosis. PvuII PP and XbaI XX genotypes may be associated with an approximately 2-fold increased DVT risk of deep vein thrombosis in men.

Original language	English
Pages (from-to)	279-280
Number of pages	2
Journal	Haematologica
Volume	91
Issue number	2
Publication status	Published - Feb 2006

Keywords

Estrogen receptor-α gene
Oral contraceptives
Polymorphisms
Thrombophilia
Venous thrombosis

ASJC Scopus subject areas

Hematology

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title = "Association of estrogen receptor-α gene polymorphisms with venous thrombosis",

abstract = "XbaI and PvuII polymorphisms of the estrogen receptor-α gene (ERα) have been associated with several multifactorial diseases. We studied the distribution of ERα polymorphisms in patients with deep vein thrombosis. PvuII PP and XbaI XX genotypes may be associated with an approximately 2-fold increased DVT risk of deep vein thrombosis in men.",

keywords = "Estrogen receptor-α gene, Oral contraceptives, Polymorphisms, Thrombophilia, Venous thrombosis",

author = "Federico Lussana and Faioni, {Elena M.} and Carmelo Mavilia and Paolo Bucciarelli and Brandi, {Maria Luisa} and Marco Cattaneo",

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T1 - Association of estrogen receptor-α gene polymorphisms with venous thrombosis

AU - Lussana, Federico

AU - Faioni, Elena M.

AU - Mavilia, Carmelo

AU - Bucciarelli, Paolo

AU - Brandi, Maria Luisa

AU - Cattaneo, Marco

PY - 2006/2

Y1 - 2006/2

N2 - XbaI and PvuII polymorphisms of the estrogen receptor-α gene (ERα) have been associated with several multifactorial diseases. We studied the distribution of ERα polymorphisms in patients with deep vein thrombosis. PvuII PP and XbaI XX genotypes may be associated with an approximately 2-fold increased DVT risk of deep vein thrombosis in men.

AB - XbaI and PvuII polymorphisms of the estrogen receptor-α gene (ERα) have been associated with several multifactorial diseases. We studied the distribution of ERα polymorphisms in patients with deep vein thrombosis. PvuII PP and XbaI XX genotypes may be associated with an approximately 2-fold increased DVT risk of deep vein thrombosis in men.

KW - Estrogen receptor-α gene

KW - Oral contraceptives

KW - Polymorphisms

KW - Thrombophilia

KW - Venous thrombosis

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