Association of estrogen receptor-α gene polymorphisms with venous thrombosis

Federico Lussana, Elena M. Faioni, Carmelo Mavilia, Paolo Bucciarelli, Maria Luisa Brandi, Marco Cattaneo

Research output: Contribution to journalArticlepeer-review

Abstract

XbaI and PvuII polymorphisms of the estrogen receptor-α gene (ERα) have been associated with several multifactorial diseases. We studied the distribution of ERα polymorphisms in patients with deep vein thrombosis. PvuII PP and XbaI XX genotypes may be associated with an approximately 2-fold increased DVT risk of deep vein thrombosis in men.

Original languageEnglish
Pages (from-to)279-280
Number of pages2
JournalHaematologica
Volume91
Issue number2
Publication statusPublished - Feb 2006

Keywords

  • Estrogen receptor-α gene
  • Oral contraceptives
  • Polymorphisms
  • Thrombophilia
  • Venous thrombosis

ASJC Scopus subject areas

  • Hematology

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