Associazione di mutazioni dell'oncogene K-RAS e delezioni del 18Q con metastasi linfonodali nel cancro del colonretto.

A. Leone; R. Pisa; R. Gasbarra; P. Graziano; D. Remotti; M. Valle; A. Garofalo

Associazione di mutazioni dell'oncogene K-RAS e delezioni del 18Q con metastasi linfonodali nel cancro del colonretto.

Translated title of the contribution: Association of mutations of K-RAS oncogene and deletions of 18Q with lymph node metastasis of colorectal cancer

A. Leone, R. Pisa, R. Gasbarra, P. Graziano, D. Remotti, M. Valle, A. Garofalo

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Molecular characterization of gastrointestinal cancer has greatly helped the definition of the key steps of the malignant transformation process and made it the best understood among the malignant cancers. Genetic influences on prognosis may have important implications for the management of the disease and help to design patient-tailored therapy. In order to acquire additional knowledge on this issue we have commenced an institutional study with the aim to identify the most frequent molecular alterations and make a correlation with the conventional histopathological parameters.

Translated title of the contribution	Association of mutations of K-RAS oncogene and deletions of 18Q with lymph node metastasis of colorectal cancer
Original language	Italian
Title of host publication	I supplementi di Tumori : official journal of Società italiana di cancerologia ... [et al.]
Volume	4
Edition	3
Publication status	Published - 2005

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Associazione di mutazioni dell'oncogene K-RAS e delezioni del 18Q con metastasi linfonodali nel cancro del colonretto. / Leone, A.; Pisa, R.; Gasbarra, R.; Graziano, P.; Remotti, D.; Valle, M.; Garofalo, A.

I supplementi di Tumori : official journal of Società italiana di cancerologia ... [et al.]. Vol. 4 3. ed. 2005.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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abstract = "Molecular characterization of gastrointestinal cancer has greatly helped the definition of the key steps of the malignant transformation process and made it the best understood among the malignant cancers. Genetic influences on prognosis may have important implications for the management of the disease and help to design patient-tailored therapy. In order to acquire additional knowledge on this issue we have commenced an institutional study with the aim to identify the most frequent molecular alterations and make a correlation with the conventional histopathological parameters.",

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AU - Graziano, P.

AU - Remotti, D.

AU - Valle, M.

AU - Garofalo, A.

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AB - Molecular characterization of gastrointestinal cancer has greatly helped the definition of the key steps of the malignant transformation process and made it the best understood among the malignant cancers. Genetic influences on prognosis may have important implications for the management of the disease and help to design patient-tailored therapy. In order to acquire additional knowledge on this issue we have commenced an institutional study with the aim to identify the most frequent molecular alterations and make a correlation with the conventional histopathological parameters.

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ER -

Associazione di mutazioni dell'oncogene K-RAS e delezioni del 18Q con metastasi linfonodali nel cancro del colonretto.

Abstract

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