Association of sarcopenia with short- and long-term mortality in older adults admitted to acute care wards: Results from the CRIME study

Davide L. Vetrano, Francesco Landi, Stefano Volpato, Andrea Corsonello, Eleonora Meloni, Roberto Bernabei, Graziano Onder

Research output: Contribution to journalArticlepeer-review

Abstract

Background. Sarcopenia is a common condition in older and frail populations, and it has been associated with adverse health outcomes. However, impact of sarcopenia on mortality in hospitalized older adults has rarely been evaluated. Aim of the present study was to investigate the association between sarcopenia and mortality during hospital stay and at 1 year after discharge in older individuals admitted to acute care wards. Methods. This is a multicentre observational study involving 770 in-hospital patients. Muscle mass was quantified with the bioelectrical impedance analysis. The diagnosis of sarcopenia was based on the algorithm proposed by the European Working Group on Sarcopenia in Older People (EWGSOP). After discharge, participants were followed for 1 year. Mortality was assessed during hospital stay and during 1-year follow-up. Results. Within the 770 participants (mean age: 81 ± 7 years, 56% women), sarcopenia was present in 214 (28%) of them, 22 participants died during hospital stay, and 113 in the year after discharge. Participants with sarcopenia had a significantly higher in-hospital (6% vs 2%; p =. 007) and 1-year mortality (26% vs 14%; p

Original languageEnglish
Pages (from-to)1154-1161
Number of pages8
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume69
Issue number9
DOIs
Publication statusPublished - 2014

Keywords

  • Acute care
  • Frailty
  • Mortality
  • Physical performance
  • Sarcopenia

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology
  • Medicine(all)

Fingerprint Dive into the research topics of 'Association of sarcopenia with short- and long-term mortality in older adults admitted to acute care wards: Results from the CRIME study'. Together they form a unique fingerprint.

Cite this