Association of vacuum-assisted closure and platelet gel for the definitive surgical repair of an enterocutaneous fistula: A case report

Marco Scala, Francesco Spagnolo, Maria Trapasso, Paolo Strada, Luciano Moresco, Pierluigi Santi

Research output: Contribution to journalArticle

Abstract

Background: Regenerative surgery deals with damaged tissue via endogenous cell activation or through autologous cell implantation. Several clinical applications employing cell infusions, platelet gel (PG), or both, are currently applied in cases in which no other therapy is application. The vacuum-assisted closure (VAC) system is a non invasive device used in the management of complicated wounds, which creates sub-atmospheric pressure promoting the wound healing process. Patients and Methods: We describe the case of a 75-year-old woman who underwent several surgical interventions and presented a non-healing ileo-cutaneous fistula. All standard procedures in order to treat the trauma failed, so a treatment associating VAC and PG was performed. Discussion and Conclusion: VAC and PG represent promising opportunities for the treatment of difficult wounds. In this case, the association of regenerative medicine using homologous PG to the VAC therapy was employed in order to enhance the effect of both techniques on tissue repair.

Original languageEnglish
Pages (from-to)147-150
Number of pages4
JournalIn Vivo
Volume26
Issue number1
Publication statusPublished - Jan 2012

Keywords

  • Fistula
  • Platelet gel
  • Regenerative surgery
  • VAC therapy
  • Wound healing

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology

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    Scala, M., Spagnolo, F., Trapasso, M., Strada, P., Moresco, L., & Santi, P. (2012). Association of vacuum-assisted closure and platelet gel for the definitive surgical repair of an enterocutaneous fistula: A case report. In Vivo, 26(1), 147-150.