Abstract
The incidence of nephrolithiasis is rising worldwide, especially in women and with increasing age. Incidence and prevalence of kidney stones are affected by genetic, nutritional, and environmental factors. The aim of this study is to investigate the link between various meteorological factors (independent variables) and the daily number of visits to the Emergency Department (ED of the S. Croce and Carle Hospital of Cuneo for renal colic (RC) and urinary stones (UC) as the dependent variable over the years 2007–2010.
The Poisson generalized regression models (PGAMs) have been used in different progressive ways. The results of PGAMs (stage 1) adjusted for seasonal and calendar factors confirmed a significant correlation (p <0.03) with the thermal parameter. Evaluation of the dose–response effect [PGAMs combined with distributed lags nonlinear models (DLNMs)—stage 2], expressed in terms of relative risk (RR) and cumulative relative risk (RRC), indicated a relative significant effect up to 15 lag days of lag (RR > 1), with a first peak after 5 days (lag ranges 0–1, 0–3, and 0–5) and a second weak peak observed along the 5–15 lag range days. The estimated RR for females was significant, mainly in the second and fourth age group considered (19–44 and >65 years): RR for total ED visits 1.27, confidence interval (CI) 1.11–1.46 (lag 0–5 days); RR 1.42, CI 1.01–2.01 (lag 0–10 days); and RR 1.35, CI 1.09–1.68 (lag 0–15 days). The research also indicated a moderate involvement of the thermal factor in the onset of RC caused by UC, exclusively in the female sex. Further studies will be necessary to confirm these results.
| Original language | English |
|---|---|
| Pages (from-to) | 249-263 |
| Number of pages | 15 |
| Journal | International Journal of Biometeorology |
| Volume | 59 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2015 |
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Keywords
- Biometeorology
- Emergency department visits
- Preventive medicine
- Renal colic
- Temperature
- Urinary calculi
ASJC Scopus subject areas
- Atmospheric Science
- Ecology
- Health, Toxicology and Mutagenesis
Cite this
Association with meteo-climatological factors and daily emergency visits for renal colic and urinary calculi in Cuneo, Italy. A retrospective observational study, 2007–2010. / Condemi, Vincenzo; Gestro, Massimo; Dozio, Elena; Tartaglino, Bruno; Corsi Romanelli, Massimiliano Marco; Solimene, Umberto; Meco, Roberto.
In: International Journal of Biometeorology, Vol. 59, No. 3, 2015, p. 249-263.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Association with meteo-climatological factors and daily emergency visits for renal colic and urinary calculi in Cuneo, Italy. A retrospective observational study, 2007–2010
AU - Condemi, Vincenzo
AU - Gestro, Massimo
AU - Dozio, Elena
AU - Tartaglino, Bruno
AU - Corsi Romanelli, Massimiliano Marco
AU - Solimene, Umberto
AU - Meco, Roberto
PY - 2015
Y1 - 2015
N2 - The incidence of nephrolithiasis is rising worldwide, especially in women and with increasing age. Incidence and prevalence of kidney stones are affected by genetic, nutritional, and environmental factors. The aim of this study is to investigate the link between various meteorological factors (independent variables) and the daily number of visits to the Emergency Department (ED of the S. Croce and Carle Hospital of Cuneo for renal colic (RC) and urinary stones (UC) as the dependent variable over the years 2007–2010.The Poisson generalized regression models (PGAMs) have been used in different progressive ways. The results of PGAMs (stage 1) adjusted for seasonal and calendar factors confirmed a significant correlation (p <0.03) with the thermal parameter. Evaluation of the dose–response effect [PGAMs combined with distributed lags nonlinear models (DLNMs)—stage 2], expressed in terms of relative risk (RR) and cumulative relative risk (RRC), indicated a relative significant effect up to 15 lag days of lag (RR > 1), with a first peak after 5 days (lag ranges 0–1, 0–3, and 0–5) and a second weak peak observed along the 5–15 lag range days. The estimated RR for females was significant, mainly in the second and fourth age group considered (19–44 and >65 years): RR for total ED visits 1.27, confidence interval (CI) 1.11–1.46 (lag 0–5 days); RR 1.42, CI 1.01–2.01 (lag 0–10 days); and RR 1.35, CI 1.09–1.68 (lag 0–15 days). The research also indicated a moderate involvement of the thermal factor in the onset of RC caused by UC, exclusively in the female sex. Further studies will be necessary to confirm these results.
AB - The incidence of nephrolithiasis is rising worldwide, especially in women and with increasing age. Incidence and prevalence of kidney stones are affected by genetic, nutritional, and environmental factors. The aim of this study is to investigate the link between various meteorological factors (independent variables) and the daily number of visits to the Emergency Department (ED of the S. Croce and Carle Hospital of Cuneo for renal colic (RC) and urinary stones (UC) as the dependent variable over the years 2007–2010.The Poisson generalized regression models (PGAMs) have been used in different progressive ways. The results of PGAMs (stage 1) adjusted for seasonal and calendar factors confirmed a significant correlation (p <0.03) with the thermal parameter. Evaluation of the dose–response effect [PGAMs combined with distributed lags nonlinear models (DLNMs)—stage 2], expressed in terms of relative risk (RR) and cumulative relative risk (RRC), indicated a relative significant effect up to 15 lag days of lag (RR > 1), with a first peak after 5 days (lag ranges 0–1, 0–3, and 0–5) and a second weak peak observed along the 5–15 lag range days. The estimated RR for females was significant, mainly in the second and fourth age group considered (19–44 and >65 years): RR for total ED visits 1.27, confidence interval (CI) 1.11–1.46 (lag 0–5 days); RR 1.42, CI 1.01–2.01 (lag 0–10 days); and RR 1.35, CI 1.09–1.68 (lag 0–15 days). The research also indicated a moderate involvement of the thermal factor in the onset of RC caused by UC, exclusively in the female sex. Further studies will be necessary to confirm these results.
KW - Biometeorology
KW - Emergency department visits
KW - Preventive medicine
KW - Renal colic
KW - Temperature
KW - Urinary calculi
UR - http://www.scopus.com/inward/record.url?scp=84939892148&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84939892148&partnerID=8YFLogxK
U2 - 10.1007/s00484-014-0861-1
DO - 10.1007/s00484-014-0861-1
M3 - Article
AN - SCOPUS:84939892148
VL - 59
SP - 249
EP - 263
JO - International Journal of Biometeorology
JF - International Journal of Biometeorology
SN - 0020-7128
IS - 3
ER -