Associations of upper limb disability measures on different levels of the international classification of functioning, disability and health in people with multiple sclerosis

Ilse Lamers, Davide Cattaneo, Christine C. Chen, Rita Bertoni, Bart Van Wijmeersch, Peter Feys

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background. It is unknown how impairments caused by multiple sclerosis (MS) affect upper limb capacity, performance, and community integration.

Objective. The aim of this study was to investigate the extent to which impairments explained the variance in activity level and participation level measures of the International Classification of Functioning, Disability and Health (ICF) and the extent to which upper limb capacity measures explained perceived performance on the activity level in people with MS and different dexterity levels.

Design. This was a cross-sectional study.

Methods. A total of 105 people with MS (median Expanded Disability Status Scale=6.5) were assessed with measures on the ICF body functions and structures level (strength, active range of motion of the wrist, tactile sensitivity, tremor, spasticity, and pain), activity level (Nine-Hole Peg Test [NHPT], Action Research Arm Test, and Manual Ability Measure-36 [MAM-36]), and participation level (Community Integration Questionnaire). The sample was divided into low- and high-dexterity subgroups on the basis of the median score on the NHPT.

Results. In the total group, muscle strength, tactile sensitivity of the thumb, and intention tremor explained 53% to 64% of the variance in activity level measures. In the low-dexterity subgroup, muscle strength and active range of motion explained 43% to 71% of the variance in activity level measures. In the high-dexterity subgroup, only 35% of the variance in the MAM-36 was explained by muscle strength. Capacity measures (NHPT and Action Research Arm Test) were moderately to highly associated with perceived performance (MAM-36) in the low-dexterity subgroup.

Limitations. Some outcome measures showed ceiling effects in people with MS and a high dexterity level.

Conclusions. Upper limb muscle strength is the most important impairment affecting capacity and perceived performance in daily life. Associations among outcome measures differ in people with MS and different dexterity levels.

Original languageEnglish
Pages (from-to)65-75
Number of pages11
JournalPhysical Therapy
Volume95
Issue number1
DOIs
Publication statusPublished - Jan 1 2015

Fingerprint

International Classification of Functioning, Disability and Health
Upper Extremity
Multiple Sclerosis
Muscle Strength
Aptitude
Community Integration
Health Services Research
Touch
Tremor
Articular Range of Motion
Outcome Assessment (Health Care)
Thumb
Wrist
Cross-Sectional Studies
Pain

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Medicine(all)

Cite this

Associations of upper limb disability measures on different levels of the international classification of functioning, disability and health in people with multiple sclerosis. / Lamers, Ilse; Cattaneo, Davide; Chen, Christine C.; Bertoni, Rita; Van Wijmeersch, Bart; Feys, Peter.

In: Physical Therapy, Vol. 95, No. 1, 01.01.2015, p. 65-75.

Research output: Contribution to journalArticle

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abstract = "Background. It is unknown how impairments caused by multiple sclerosis (MS) affect upper limb capacity, performance, and community integration.Objective. The aim of this study was to investigate the extent to which impairments explained the variance in activity level and participation level measures of the International Classification of Functioning, Disability and Health (ICF) and the extent to which upper limb capacity measures explained perceived performance on the activity level in people with MS and different dexterity levels.Design. This was a cross-sectional study.Methods. A total of 105 people with MS (median Expanded Disability Status Scale=6.5) were assessed with measures on the ICF body functions and structures level (strength, active range of motion of the wrist, tactile sensitivity, tremor, spasticity, and pain), activity level (Nine-Hole Peg Test [NHPT], Action Research Arm Test, and Manual Ability Measure-36 [MAM-36]), and participation level (Community Integration Questionnaire). The sample was divided into low- and high-dexterity subgroups on the basis of the median score on the NHPT.Results. In the total group, muscle strength, tactile sensitivity of the thumb, and intention tremor explained 53{\%} to 64{\%} of the variance in activity level measures. In the low-dexterity subgroup, muscle strength and active range of motion explained 43{\%} to 71{\%} of the variance in activity level measures. In the high-dexterity subgroup, only 35{\%} of the variance in the MAM-36 was explained by muscle strength. Capacity measures (NHPT and Action Research Arm Test) were moderately to highly associated with perceived performance (MAM-36) in the low-dexterity subgroup.Limitations. Some outcome measures showed ceiling effects in people with MS and a high dexterity level.Conclusions. Upper limb muscle strength is the most important impairment affecting capacity and perceived performance in daily life. Associations among outcome measures differ in people with MS and different dexterity levels.",
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