Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial

C. Eng; T.W. Kim; J. Bendell; G. Argilés; N.C. Tebbutt; M. Di Bartolomeo; A. Falcone; M. Fakih; M. Kozloff; N.H. Segal; A. Sobrero; Y. Yan; I. Chang; A. Uyei; L. Roberts; F. Ciardiello; J.B. Ahn; J. Asselah; S. Badarinath; S. Baijal; S. Begbie; S. Berry; J.L. Canon; R.G. Carbone; A. Cervantes; Y.J. Cha; K. Chang; A. Chaudhry; E. Chmielowska; S.H. Cho; D. Chu; F. Couture; J. Cultrera; D. Cunningham; E. Van Cutsem; P.J. Cuyle; J. Davies; S. Dowden; M. Dvorkin; V. Ganju; R.V. Garcia; R. Kerr; T.Y. Kim; K. King; J. Kortmansky; K.O. Lam; J. Lee; A.S. Lee; B. Lesperance; E. Maiello

doi:10.1016/S1470-2045(19)30027-0

Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial

C. Eng, T.W. Kim, J. Bendell, G. Argilés, N.C. Tebbutt, M. Di Bartolomeo, A. Falcone, M. Fakih, M. Kozloff, N.H. Segal, A. Sobrero, Y. Yan, I. Chang, A. Uyei, L. Roberts, F. Ciardiello, J.B. Ahn, J. Asselah, S. Badarinath, S. BaijalS. Begbie, S. Berry, J.L. Canon, R.G. Carbone, A. Cervantes, Y.J. Cha, K. Chang, A. Chaudhry, E. Chmielowska, S.H. Cho, D. Chu, F. Couture, J. Cultrera, D. Cunningham, E. Van Cutsem, P.J. Cuyle, J. Davies, S. Dowden, M. Dvorkin, V. Ganju, R.V. Garcia, R. Kerr, T.Y. Kim, K. King, J. Kortmansky, K.O. Lam, J. Lee, A.S. Lee, B. Lesperance, E. Maiello

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	849-861
Number of pages	13
Journal	The Lancet Oncology
Volume	20
Issue number	6
DOIs	https://doi.org/10.1016/S1470-2045(19)30027-0
Publication status	Published - 2019

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10.1016/S1470-2045(19)30027-0

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85066145160&doi=10.1016%2fS1470-2045%2819%2930027-0&partnerID=40&md5=1035e5f8777d2dc731de8d4a6c7ba5fa

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Eng, C., Kim, T. W., Bendell, J., Argilés, G., Tebbutt, N. C., Di Bartolomeo, M., Falcone, A., Fakih, M., Kozloff, M., Segal, N. H., Sobrero, A., Yan, Y., Chang, I., Uyei, A., Roberts, L., Ciardiello, F., Ahn, J. B., Asselah, J., Badarinath, S., ... Maiello, E. (2019). Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial. The Lancet Oncology, 20(6), 849-861. https://doi.org/10.1016/S1470-2045(19)30027-0

Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial. / Eng, C.; Kim, T.W.; Bendell, J.; Argilés, G.; Tebbutt, N.C.; Di Bartolomeo, M.; Falcone, A.; Fakih, M.; Kozloff, M.; Segal, N.H.; Sobrero, A.; Yan, Y.; Chang, I.; Uyei, A.; Roberts, L.; Ciardiello, F.; Ahn, J.B.; Asselah, J.; Badarinath, S.; Baijal, S.; Begbie, S.; Berry, S.; Canon, J.L.; Carbone, R.G.; Cervantes, A.; Cha, Y.J.; Chang, K.; Chaudhry, A.; Chmielowska, E.; Cho, S.H.; Chu, D.; Couture, F.; Cultrera, J.; Cunningham, D.; Van Cutsem, E.; Cuyle, P.J.; Davies, J.; Dowden, S.; Dvorkin, M.; Ganju, V.; Garcia, R.V.; Kerr, R.; Kim, T.Y.; King, K.; Kortmansky, J.; Lam, K.O.; Lee, J.; Lee, A.S.; Lesperance, B.; Maiello, E.

In: The Lancet Oncology, Vol. 20, No. 6, 2019, p. 849-861.

Research output: Contribution to journal › Article › peer-review

Eng, C, Kim, TW, Bendell, J, Argilés, G, Tebbutt, NC, Di Bartolomeo, M , Falcone, A, Fakih, M, Kozloff, M, Segal, NH, Sobrero, A, Yan, Y, Chang, I, Uyei, A, Roberts, L, Ciardiello, F, Ahn, JB, Asselah, J, Badarinath, S, Baijal, S, Begbie, S, Berry, S, Canon, JL, Carbone, RG, Cervantes, A, Cha, YJ, Chang, K, Chaudhry, A, Chmielowska, E, Cho, SH, Chu, D, Couture, F, Cultrera, J, Cunningham, D, Van Cutsem, E, Cuyle, PJ, Davies, J, Dowden, S, Dvorkin, M, Ganju, V, Garcia, RV, Kerr, R, Kim, TY, King, K, Kortmansky, J, Lam, KO, Lee, J, Lee, AS, Lesperance, B & Maiello, E 2019, 'Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial', The Lancet Oncology, vol. 20, no. 6, pp. 849-861. https://doi.org/10.1016/S1470-2045(19)30027-0

Eng, C. ; Kim, T.W. ; Bendell, J. ; Argilés, G. ; Tebbutt, N.C. ; Di Bartolomeo, M. ; Falcone, A. ; Fakih, M. ; Kozloff, M. ; Segal, N.H. ; Sobrero, A. ; Yan, Y. ; Chang, I. ; Uyei, A. ; Roberts, L. ; Ciardiello, F. ; Ahn, J.B. ; Asselah, J. ; Badarinath, S. ; Baijal, S. ; Begbie, S. ; Berry, S. ; Canon, J.L. ; Carbone, R.G. ; Cervantes, A. ; Cha, Y.J. ; Chang, K. ; Chaudhry, A. ; Chmielowska, E. ; Cho, S.H. ; Chu, D. ; Couture, F. ; Cultrera, J. ; Cunningham, D. ; Van Cutsem, E. ; Cuyle, P.J. ; Davies, J. ; Dowden, S. ; Dvorkin, M. ; Ganju, V. ; Garcia, R.V. ; Kerr, R. ; Kim, T.Y. ; King, K. ; Kortmansky, J. ; Lam, K.O. ; Lee, J. ; Lee, A.S. ; Lesperance, B. ; Maiello, E. / Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial. In: The Lancet Oncology. 2019 ; Vol. 20, No. 6. pp. 849-861.

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title = "Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial",

author = "C. Eng and T.W. Kim and J. Bendell and G. Argil{\'e}s and N.C. Tebbutt and {Di Bartolomeo}, M. and A. Falcone and M. Fakih and M. Kozloff and N.H. Segal and A. Sobrero and Y. Yan and I. Chang and A. Uyei and L. Roberts and F. Ciardiello and J.B. Ahn and J. Asselah and S. Badarinath and S. Baijal and S. Begbie and S. Berry and J.L. Canon and R.G. Carbone and A. Cervantes and Y.J. Cha and K. Chang and A. Chaudhry and E. Chmielowska and S.H. Cho and D. Chu and F. Couture and J. Cultrera and D. Cunningham and {Van Cutsem}, E. and P.J. Cuyle and J. Davies and S. Dowden and M. Dvorkin and V. Ganju and R.V. Garcia and R. Kerr and T.Y. Kim and K. King and J. Kortmansky and K.O. Lam and J. Lee and A.S. Lee and B. Lesperance and E. Maiello",

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T1 - Atezolizumab with or without cobimetinib versus regorafenib in previously treated metastatic colorectal cancer (IMblaze370): a multicentre, open-label, phase 3, randomised, controlled trial

AU - Eng, C.

AU - Kim, T.W.

AU - Bendell, J.

AU - Argilés, G.

AU - Tebbutt, N.C.

AU - Di Bartolomeo, M.

AU - Falcone, A.

AU - Fakih, M.

AU - Kozloff, M.

AU - Segal, N.H.

AU - Sobrero, A.

AU - Yan, Y.

AU - Chang, I.

AU - Uyei, A.

AU - Roberts, L.

AU - Ciardiello, F.

AU - Ahn, J.B.

AU - Asselah, J.

AU - Badarinath, S.

AU - Baijal, S.

AU - Begbie, S.

AU - Berry, S.

AU - Canon, J.L.

AU - Carbone, R.G.

AU - Cervantes, A.

AU - Cha, Y.J.

AU - Chang, K.

AU - Chaudhry, A.

AU - Chmielowska, E.

AU - Cho, S.H.

AU - Chu, D.

AU - Couture, F.

AU - Cultrera, J.

AU - Cunningham, D.

AU - Van Cutsem, E.

AU - Cuyle, P.J.

AU - Davies, J.

AU - Dowden, S.

AU - Dvorkin, M.

AU - Ganju, V.

AU - Garcia, R.V.

AU - Kerr, R.

AU - Kim, T.Y.

AU - King, K.

AU - Kortmansky, J.

AU - Lam, K.O.

AU - Lee, J.

AU - Lee, A.S.

AU - Lesperance, B.

AU - Maiello, E.

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DO - 10.1016/S1470-2045(19)30027-0

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