Atopic dermatitis - All you can do from the outside

C. Gelmetti, A. Wollenberg

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Atopic dermatitis (AD) affects both the epidermal barrier and the immune system and, as such, therapy needs to address both. Skin cleansing supported by emollients and moisturizers is the primary topical therapy when treating patients with AD. However, it should be remembered that the direct use of emollients on inflamed skin is poorly tolerated and that the flares need to be treated effectively, usually by topical corticosteroids (TCS) and/or topical calcineurin inhibitors (TCI). This contribution outlines a number of strategies for effectively managing AD, from reactive therapy using TCS and TCI to proactive therapy. Proactive therapy is an alternative, evidence-based, immunologically founded treatment approach, based on the fact that normal-looking, nonlesional skin of patients with AD is not normal. The advantage of the proactive approach is that the patients are in control of their disease and are actively involved in its management. The avoidance of external irritants is recommended wherever possible.

Original languageEnglish
Pages (from-to)19-24
Number of pages6
JournalBritish Journal of Dermatology
Volume170
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 2014

Fingerprint

Atopic Dermatitis
Emollients
Skin
Adrenal Cortex Hormones
Therapeutics
Irritants
Complementary Therapies
Immune System
Calcineurin Inhibitors

ASJC Scopus subject areas

  • Dermatology
  • Medicine(all)

Cite this

Atopic dermatitis - All you can do from the outside. / Gelmetti, C.; Wollenberg, A.

In: British Journal of Dermatology, Vol. 170, No. SUPPL. 1, 2014, p. 19-24.

Research output: Contribution to journalArticle

Gelmetti, C. ; Wollenberg, A. / Atopic dermatitis - All you can do from the outside. In: British Journal of Dermatology. 2014 ; Vol. 170, No. SUPPL. 1. pp. 19-24.
@article{8602de3da3d8475c8d49307885efc8f5,
title = "Atopic dermatitis - All you can do from the outside",
abstract = "Atopic dermatitis (AD) affects both the epidermal barrier and the immune system and, as such, therapy needs to address both. Skin cleansing supported by emollients and moisturizers is the primary topical therapy when treating patients with AD. However, it should be remembered that the direct use of emollients on inflamed skin is poorly tolerated and that the flares need to be treated effectively, usually by topical corticosteroids (TCS) and/or topical calcineurin inhibitors (TCI). This contribution outlines a number of strategies for effectively managing AD, from reactive therapy using TCS and TCI to proactive therapy. Proactive therapy is an alternative, evidence-based, immunologically founded treatment approach, based on the fact that normal-looking, nonlesional skin of patients with AD is not normal. The advantage of the proactive approach is that the patients are in control of their disease and are actively involved in its management. The avoidance of external irritants is recommended wherever possible.",
author = "C. Gelmetti and A. Wollenberg",
year = "2014",
doi = "10.1111/bjd.12957",
language = "English",
volume = "170",
pages = "19--24",
journal = "British Journal of Dermatology",
issn = "0007-0963",
publisher = "Blackwell Publishing Ltd",
number = "SUPPL. 1",

}

TY - JOUR

T1 - Atopic dermatitis - All you can do from the outside

AU - Gelmetti, C.

AU - Wollenberg, A.

PY - 2014

Y1 - 2014

N2 - Atopic dermatitis (AD) affects both the epidermal barrier and the immune system and, as such, therapy needs to address both. Skin cleansing supported by emollients and moisturizers is the primary topical therapy when treating patients with AD. However, it should be remembered that the direct use of emollients on inflamed skin is poorly tolerated and that the flares need to be treated effectively, usually by topical corticosteroids (TCS) and/or topical calcineurin inhibitors (TCI). This contribution outlines a number of strategies for effectively managing AD, from reactive therapy using TCS and TCI to proactive therapy. Proactive therapy is an alternative, evidence-based, immunologically founded treatment approach, based on the fact that normal-looking, nonlesional skin of patients with AD is not normal. The advantage of the proactive approach is that the patients are in control of their disease and are actively involved in its management. The avoidance of external irritants is recommended wherever possible.

AB - Atopic dermatitis (AD) affects both the epidermal barrier and the immune system and, as such, therapy needs to address both. Skin cleansing supported by emollients and moisturizers is the primary topical therapy when treating patients with AD. However, it should be remembered that the direct use of emollients on inflamed skin is poorly tolerated and that the flares need to be treated effectively, usually by topical corticosteroids (TCS) and/or topical calcineurin inhibitors (TCI). This contribution outlines a number of strategies for effectively managing AD, from reactive therapy using TCS and TCI to proactive therapy. Proactive therapy is an alternative, evidence-based, immunologically founded treatment approach, based on the fact that normal-looking, nonlesional skin of patients with AD is not normal. The advantage of the proactive approach is that the patients are in control of their disease and are actively involved in its management. The avoidance of external irritants is recommended wherever possible.

UR - http://www.scopus.com/inward/record.url?scp=84902837193&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902837193&partnerID=8YFLogxK

U2 - 10.1111/bjd.12957

DO - 10.1111/bjd.12957

M3 - Article

C2 - 24720530

AN - SCOPUS:84902837193

VL - 170

SP - 19

EP - 24

JO - British Journal of Dermatology

JF - British Journal of Dermatology

SN - 0007-0963

IS - SUPPL. 1

ER -