Atrial fibrillation burden during the post-implant period after CRT using device-based diagnostics

Burkhard Hügl, Hans Jürgen Bruns, Christine Unterberg-Buchwald, Anett Grosse, Berthold Stegemann, Bernward Lauer, J. Christoph Geller, Maurizio Gasparini

Research output: Contribution to journalArticlepeer-review


Aims: Cardiac resynchronization therapy (CRT) is increasingly used in congestive heart failure (CHF) patients (with cardiac dyssynchrony). In addition to delivering therapy, CRT devices offer a variety of diagnostic tools for continuous long-term monitoring of clinically relevant information (i.e., occurrence and duration of arrhythmia episodes). Methods and Results: Eighty-four patients with drug-refractory CHF in NYHA-class II-IV received a CRT device. The response to CRT was assessed by determining NYHA class at baseline and at 3 months follow-up. Atrial fibrillation (AF) burden (defined as time of AF per day) was continuously measured by the device. A significant gradual reduction of AF burden (from 9.88 ± 12.61 to 4.20 ± 9.24 [hours/day]) and number of patients experiencing AF episodes (from 26 to 13) were observed during CRT. Conclusions: (1) Diagnostic features for long-term monitoring of physiological variables provide useful information on the state and course of AF and may improve disease management. (2) AF burden reduces over time during the first 3 months after CRT implantation.

Original languageEnglish
Pages (from-to)813-817
Number of pages5
JournalJournal of Cardiovascular Electrophysiology
Issue number8
Publication statusPublished - Aug 2006


  • Atrial fibrillation
  • Biventricular pacing
  • Cardiac resynchronization
  • Congestive heart failure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology


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