Atrial natriuretic peptide and related peptides

Yoshihiro J. Akashi, Jochen Springer, Mitja Lainscak, Stefan D. Anker

Research output: Contribution to journalArticlepeer-review

Abstract

In recent years, biomarkers have been recognized as important tools for diagnosis, risk stratification, and therapeutic decision-making in cardiovascular diseases. Currently, the clinical potential of several natriuretic peptides is under scientific investigation. The well-known counter-regulatory hormones are atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP), dendroaspis natriuretic peptide (DNP) and urodilatin, which play an important role in the homeostasis of body fluid volume. ANP and BNP have already been demonstrated to have diagnostic usefulness in a great number of studies, which have progressed from bench to bedside. This article summarizes existing data on ANP and related peptides in cardiovascular and other disorders, and outlines the potential clinical usefulness of these markers.

Original languageEnglish
Pages (from-to)1259-1267
Number of pages9
JournalClinical Chemistry and Laboratory Medicine
Volume45
Issue number10
DOIs
Publication statusPublished - Oct 1 2007

Keywords

  • Acute coronary syndrome
  • Atrial natriuretic peptide (ANP)
  • Brain natriuretic peptide (BNP)
  • C-type natriuretic peptide (CNP)
  • Dendroaspis natriuretic peptide (DNP)
  • Heart failure
  • Renal failure

ASJC Scopus subject areas

  • Clinical Biochemistry

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