Atrial natriuretic peptides and renin release

A. Mark Richards, Giancarlo Tonolo, Malcolm Tree, J. Ian S Robertson, Piero Montorsi, Brenda J. Leckie, Jorge Polonia

Research output: Contribution to journalArticlepeer-review


The relationship between endogenous plasma concentrations of atrial natriuretic peptide and renin was examined in resting normal subjects and patients with cardiac impairment. To test the hypothesis that atrial natriuretic peptide inhibits renin secretion, intravenous infusions of atrial natriuretic peptide were administered to normal volunteers, patients with end-stage renal failure, and conscious dogs in both sodium-replete and sodium-depleted states. Plasma atrial natriuretic peptide and renin were inversely related in normal subjects (r = -0.52, n = 140, p

Original languageEnglish
Pages (from-to)112-118
Number of pages7
JournalAmerican Journal of Medicine
Issue number3 SUPPL. 1
Publication statusPublished - Mar 11 1988

ASJC Scopus subject areas

  • Nursing(all)


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