Abstract
Considering the role of precancerosis played by atrophic gastritis and the high value of its incidence in people in the 40 to 60 age group, the authors wished to report the results of a mass screening undertaken on carriers of this affection and of the organisation of a follow-up programme and especially of patients carrying atrophic gastritis with intestinal metaplasia, a defined high-risk situation. It is to this end that the determination of the fasting serum gastrin was first of all used. This was followed in presence of greater values than as normal, by basal gastroacidogram and after histamine stimulation and gastroscopy with multiple biopsies for a histological, immunological and enzymological examination. The determination of lactatodehydrogenas, more especially, showed itself very valid in screening, at an initial stage, the malignant transformation of an atrophic gastritis with a high degree of intestinal metaplasia.
| Translated title of the contribution | Atrophic gastritis: mass screening and follow-up of high - Risk subjects |
|---|---|
| Original language | French |
| Pages (from-to) | 111-122 |
| Number of pages | 12 |
| Journal | Acta Endoscopica |
| Volume | 8 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Mar 1978 |
Keywords
- atrophic gastritis
- early cancer
- intestinal metaplasia
- isoenzymes
- lactatedehydrogenase
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Medicine(all)