Attitude towards genetic testing for breast cancer susceptibility: A comparison of affected and unaffected women

M. Bruno, M. Digennaro, S. Tommasi, B. Stea, T. Danese, F. Schittulli, A. Paradiso

Research output: Contribution to journalArticle

Abstract

The objective of this study is to evaluate women's awareness and interest in genetic testing for breast cancer risk, to identify socio-demographic factors, to analyse the reasons for wanting or not wanting to be tested and finally to determine whether breast cancer patients and healthy women have different attitudes towards genetic testing. Consecutive series of 879 women without and with breast cancer participated in a 20-item self-completing questionnaire. Among breast cancer patients, 57% answered that they would definitely or probably accept being tested, compared with 84% of women without breast cancer. At the multiple logistic regression analysis only to have a diagnosis of breast cancer conditioned significantly the interest to have genetic testing. Surprisingly, a family history of breast cancer was found to have no significant impact. The most frequently cited reason for being interested in genetic testing was 'to learn about your children's risk'. Although women's awareness about breast cancer genes is inadequate, the interest in genetic testing is substantial and higher both in healthy women and in women with breast cancer. These results provide important indications for the development of educational strategies.

Original languageEnglish
Pages (from-to)360-368
Number of pages9
JournalEuropean Journal of Cancer Care
Volume19
Issue number3
DOIs
Publication statusPublished - May 2010

Keywords

  • Breast cancer
  • Family health history
  • Genetic testing
  • Interest
  • Survey

ASJC Scopus subject areas

  • Oncology

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