Atypical carcinoid with prominent mucinous stroma: A hitherto unreported variant of pulmonary neuroendocrine tumor

Nazarena Nannini, Federica Bertolini, Alberto Cavazza, Christian Casali, Maria Cecilia Mengoli, Giulio Rossi

Research output: Contribution to journalArticlepeer-review

Abstract

Carcinoid tumors of the lung may show several growth patterns and cell types. We report here a previously undescribed case of primary pulmonary atypical carcinoid with prominent mucinous stroma, an exceedingly rare variant of carcinoid tumor so far reported only in the thymus. The tumor was discovered in a 50-year-old, non-smoker woman, and pursued an aggressive behavior. The lack of TTF-1 expression and the positive staining with hormonal receptors made the diagnosis very challenging. Differential diagnosis with other primary and metastatic mucin-rich tumors is also discussed.

Original languageEnglish
Pages (from-to)120-124
Number of pages5
JournalEndocrine Pathology
Volume21
Issue number2
DOIs
Publication statusPublished - Jun 2010

Keywords

  • Atypical
  • Carcinoid
  • Estrogen receptor
  • Lung
  • Mucus

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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