Atypical fibroxanthoma with osteoclast-like multinucleated giant cells

Nicola Ferrara, Gianluca Baldi, Maria Pia D I Marino, Giuseppe Bellucci, Alfonso Baldi

Research output: Contribution to journalArticlepeer-review


Atypical fibroxanthoma (AF) is generally considered as a low grade superficial variant of fibrohistiocytic neoplasm. In this report we present an unusual variant of this neoplasm arising from actinic damaged skin of an elderly individual. The case was characterized by numerous multinucleated osteoclast-like giant cells uniformly scattered through a pleomorfic cellular proliferation. The osteoclasts giant cell observed represent multinucleated histiocytes rather than true osteoclasts.

Original languageEnglish
Pages (from-to)105-107
Number of pages3
JournalIn Vivo
Issue number1
Publication statusPublished - Jan 2000


  • Atypical fibroxanthoma
  • Cutaneous fibrous histocytoma
  • Osteoclast-like giant cells tumour

ASJC Scopus subject areas

  • Medicine(all)


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