Abstract
The hematological and cytogenetical studies of a case of atypical myeloproliferative disorder are reported. The patient displayed moderate leukocytosis, anemia and thrombocytopenia. Reduced or absent growth of CFU-C was observed in the bone marrow and peripheral blood. The cytogenetical analysis revealed a trisomy 21 limited to the neoplastic clone. The overall results are discussed and compared with the rare cases of acquired trisomy 21 reported in the literature.
Original language | English |
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Pages (from-to) | 111-115 |
Number of pages | 5 |
Journal | La Ricerca in Clinica e in Laboratorio |
Volume | 11 |
Issue number | 2 |
DOIs | |
Publication status | Published - Apr 1981 |
Keywords
- Chromosomal banding
- Chromosomal marker
- Chronic myeloid leukemia
- Myeloproliferative disorder
- Trisomy 21 clone
ASJC Scopus subject areas
- Clinical Biochemistry