Atypical myeloproliferative disorder associated with a 21 trisomic clone

Giorgio Ponzio; Massimo Aglietta; Wanda Piacibello; Mario De Marchi; Angelo O. Carbonara

doi:10.1007/BF02886709

Atypical myeloproliferative disorder associated with a 21 trisomic clone

Giorgio Ponzio, Massimo Aglietta, Wanda Piacibello, Mario De Marchi, Angelo O. Carbonara

Istituto Oncologico Candiolo

Research output: Contribution to journal › Article › peer-review

Abstract

The hematological and cytogenetical studies of a case of atypical myeloproliferative disorder are reported. The patient displayed moderate leukocytosis, anemia and thrombocytopenia. Reduced or absent growth of CFU-C was observed in the bone marrow and peripheral blood. The cytogenetical analysis revealed a trisomy 21 limited to the neoplastic clone. The overall results are discussed and compared with the rare cases of acquired trisomy 21 reported in the literature.

Original language	English
Pages (from-to)	111-115
Number of pages	5
Journal	La Ricerca in Clinica e in Laboratorio
Volume	11
Issue number	2
DOIs	https://doi.org/10.1007/BF02886709
Publication status	Published - Apr 1981

Keywords

Chromosomal banding
Chromosomal marker
Chronic myeloid leukemia
Myeloproliferative disorder
Trisomy 21 clone

ASJC Scopus subject areas

Clinical Biochemistry

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10.1007/BF02886709

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title = "Atypical myeloproliferative disorder associated with a 21 trisomic clone",

abstract = "The hematological and cytogenetical studies of a case of atypical myeloproliferative disorder are reported. The patient displayed moderate leukocytosis, anemia and thrombocytopenia. Reduced or absent growth of CFU-C was observed in the bone marrow and peripheral blood. The cytogenetical analysis revealed a trisomy 21 limited to the neoplastic clone. The overall results are discussed and compared with the rare cases of acquired trisomy 21 reported in the literature.",

keywords = "Chromosomal banding, Chromosomal marker, Chronic myeloid leukemia, Myeloproliferative disorder, Trisomy 21 clone",

author = "Giorgio Ponzio and Massimo Aglietta and Wanda Piacibello and {De Marchi}, Mario and Carbonara, {Angelo O.}",

year = "1981",

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AU - Ponzio, Giorgio

AU - Aglietta, Massimo

AU - Piacibello, Wanda

AU - De Marchi, Mario

AU - Carbonara, Angelo O.

PY - 1981/4

Y1 - 1981/4

N2 - The hematological and cytogenetical studies of a case of atypical myeloproliferative disorder are reported. The patient displayed moderate leukocytosis, anemia and thrombocytopenia. Reduced or absent growth of CFU-C was observed in the bone marrow and peripheral blood. The cytogenetical analysis revealed a trisomy 21 limited to the neoplastic clone. The overall results are discussed and compared with the rare cases of acquired trisomy 21 reported in the literature.

AB - The hematological and cytogenetical studies of a case of atypical myeloproliferative disorder are reported. The patient displayed moderate leukocytosis, anemia and thrombocytopenia. Reduced or absent growth of CFU-C was observed in the bone marrow and peripheral blood. The cytogenetical analysis revealed a trisomy 21 limited to the neoplastic clone. The overall results are discussed and compared with the rare cases of acquired trisomy 21 reported in the literature.

KW - Chromosomal banding

KW - Chromosomal marker

KW - Chronic myeloid leukemia

KW - Myeloproliferative disorder

KW - Trisomy 21 clone

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Atypical myeloproliferative disorder associated with a 21 trisomic clone

Abstract

Keywords

ASJC Scopus subject areas

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