New studies suggest that Mycoplasma pneumoniae and Chlamydia pneumoniae play a more significant role as causes of lower respiratory tract infections in childhood than was previously thought. In particular, the incidence of the infections caused by these pathogens is high in children aged less than five years, and the infections themselves seem to be a possible cause of wheezing as well as pharyngitis and may present a more complicated course when not treated with adequate antimicrobial agents. However, despite the increasing pathogenic significance of M. pneumoniae and C. pneumoniae, progress in fighting them is hampered by the lack of rapid and standardised diagnostic methods. This not only renders it practically impossible for practitioners to make a specific microbiological diagnosis, but has also had an adverse effect on treatment trials and generated some questionable results. Carefully randomised and controlled trials are clearly needed to examine the effectiveness of different antibiotics against M. pneumoniae or C. pneumoniae, and the optimal duration of therapy in various patient groups.
|Translated title of the contribution||Atypical phatogens and respiratory infections in childrens|
|Number of pages||9|
|Journal||GIMT - Giornale Italiano delle Malattie del Torace|
|Publication status||Published - 2002|
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine