"Atypical steroid response" in a pulmonary inflammatory myofibroblastic tumor

Oliviero Sacco, Claudio Gambini, Chiara Gardella, Paolo Tomà, Umberto G. Rossi, Vincenzo Jasonni, Andrew Bush, Giovanni A. Rossi

Research output: Contribution to journalArticlepeer-review


A 6-year-old girl was evaluated for the presence of a paratracheal mass with right upper lobe atelectasis due to an endobronchial mass. Bronchoscopic biopsy established a diagnosis of inflammatory myofibroblastic tumor (IMT) and prednisone initially led to a significant reduction of the endobronchial lesion. However, 8 weeks later, when still on prednisone, the mediastinal mass enlarged dramatically. At thoracotomy, a well-circumscribed, multilobulated mass was partially resected and a diagnosis of IMT confirmed. Immunosuppression by corticosteroids may have favored the rapid progression of this apparently benign, indolent tumor.

Original languageEnglish
Pages (from-to)721-726
Number of pages6
JournalPediatric Pulmonology
Issue number7
Publication statusPublished - Jul 2010


  • Atelectasis
  • Inflammatory myofibroblastic tumor
  • Mediastinal mass
  • Plasma cell granuloma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine


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