Autochthonous human alveolar echinococcosis in a Hungarian patient

Bal�zs Dezs�nyi, Tam�s Strausz, Zita Makrai, Judit Csomor, J�zsef Danka, Peter Kern, Giovanni Rezza, Thomas F.E. Barth, Adriano Casulli

Research output: Contribution to journalArticlepeer-review


Background: Alveolar echinococcosis is a zoonotic parasitic disease causing a severe clinical condition and is known as the most deadly of all helminth infections. Moreover, this disease is also an increasing concern in Northern and Eastern Europe due to its spread in the wildlife animal host. Case presentation: An asymptomatic 70-year-old woman from south-western Hungary was diagnosed with multiple liver lesions. Imaging techniques (ultrasound, computed tomography and magnetic resonance imaging), serology (ELISA, indirect hemagglutination and Western blot), and conventional staining methods (hematoxylin–eosin and periodic acid–Schiff) were used for the detection of the disease. A histopathological re-evaluation of formalin-fixed paraffin block by immunohistochemical staining with the monoclonal antibody Em2G11 definitively confirmed the diagnosis of alveolar echinococcosis. Conclusions: To our knowledge, this is the first confirmed autochthonous case of human alveolar echinococcosis in Hungary. To what extent diagnostic difficulties may contribute to underestimate this zoonosis in Eastern Europe is unknown. Differential diagnosis with alveolar echinococcosis should be considered for patients with multiple, tumor-like cystic lesions of the liver, in countries where this parasite is emerging.

Original languageEnglish
Pages (from-to)107-110
Number of pages4
Issue number1
Publication statusPublished - Feb 1 2017


  • Alveolar echinococcosis
  • Case report
  • Differential diagnosis
  • Echinococcus multilocularis
  • Histopathological re-evaluation
  • Public health threat

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


Dive into the research topics of 'Autochthonous human alveolar echinococcosis in a Hungarian patient'. Together they form a unique fingerprint.

Cite this