Autofluorescence removal from fluorescence molecular tomography data

Giannis Zacharakis, Anikitos Garofalakis, Stelios Psycharakis, Heiko Meyer, Clio Mamalaki, Georgia Fousteri, Joseph Papamatheakis, Dimitris Kioussis, Vasilis Ntziachristos, Eleftherios N. Economou, Jorge Ripoll

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present a study on three-dimensional mapping and removal of autofluorescence from fluorescence molecular tomography (FMT) data, both for phantoms and small animal in vivo measurements. The technique is based on the recording of tomographic data in multiple spectral regions with different excitation light and on the application of a linear unmixing algorithm for targeting multiple fluorescent probes. Autofluorescence spectra are recorded using an identical reflection geometry as during the FMT acquisitions.

Original languageEnglish
Title of host publicationOptics InfoBase Conference Papers
PublisherOptical Society of America
ISBN (Print)1557528071, 9781557528070
Publication statusPublished - 2006
EventBiomedical Topical Meeting, BIO 2006 - Fort Lauderdale, FL, United States
Duration: Mar 19 2006Mar 19 2006

Other

OtherBiomedical Topical Meeting, BIO 2006
CountryUnited States
CityFort Lauderdale, FL
Period3/19/063/19/06

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

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  • Cite this

    Zacharakis, G., Garofalakis, A., Psycharakis, S., Meyer, H., Mamalaki, C., Fousteri, G., Papamatheakis, J., Kioussis, D., Ntziachristos, V., Economou, E. N., & Ripoll, J. (2006). Autofluorescence removal from fluorescence molecular tomography data. In Optics InfoBase Conference Papers Optical Society of America.