Diagnosis of autoimmune hepatitis (AH) is based on: Exclusion of viral genetic or tossic etiology, presence of non-organ-specific antibodies (SMA, ANA or LKM1); increased G immunoglobulin, typical histological features; response to immunosuppressive therapy, severity and immunogenetic background, 21 cases, observed over 20 years, are reported. They represent different types of AH: Type 1, isolated (or lupoid, SMA positive); type 2, LKM1 positive, often associated with autoimmune polyglandular syndromes; coeliac hepatitis (or idyopatic hypertransaminasaemia); type 1 AH associated to coeliac disease; giant-cell hepatitis, Coombs test positive; AH following liver transplantation (de novo hepatitis); autoimmune cholangitis associated with chronic inflammatory bowel disease.
|Translated title of the contribution||Autoimmune hepatitis in the year 2000|
|Number of pages||10|
|Journal||Medico e Bambino|
|Publication status||Published - Oct 31 2001|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health