Autologous bone marrow transplantation in patients with non-Hodgkin's lymphoma: Comparison of different parameters in predicting the kinetics of haematological recovery

G. Visani, A. Dinota, F. Verlicchi, G. Bandini, P. Ricci, M. R. Motta, S. Rizzi, R. M. Lemoli, C. Poluzzi, F. Gherlinzoni, E. Calori, P. Mazza, S. Tura

Research output: Contribution to journalArticle

Abstract

We analysed the kinetics of haematological recovery after autologous bone marrow transplantation (ABMT) in 31 patients with non-Hodgkin's lymphoma, of whom 14 had received chemotherapy and 17 had received no chemotherapy before marrow harvesting. The time for recovery of polymorph (PMN) and platelet numbers was assessed in relation to patient's sex, age, the numbers of mononuclear cells (MNC) and of granulocyte-macrophage colony-forming cells (CFU-GM) reinfused, the therapy before harvesting and the conditioning regimens. The results showed that the most important factor influencing the speed of haematological recovery was therapy before marrow collection; recovery was faster in patients not treated before harvesting than in those treated. The mean day for PMN recovery to 0.5 x 109/l was 14.6 vs 21.8 (p9/l was 16.5 vs 44.4 (p

Original languageEnglish
Pages (from-to)599-605
Number of pages7
JournalBone Marrow Transplantation
Volume3
Issue number6
Publication statusPublished - 1988

    Fingerprint

ASJC Scopus subject areas

  • Hematology
  • Transplantation

Cite this

Visani, G., Dinota, A., Verlicchi, F., Bandini, G., Ricci, P., Motta, M. R., Rizzi, S., Lemoli, R. M., Poluzzi, C., Gherlinzoni, F., Calori, E., Mazza, P., & Tura, S. (1988). Autologous bone marrow transplantation in patients with non-Hodgkin's lymphoma: Comparison of different parameters in predicting the kinetics of haematological recovery. Bone Marrow Transplantation, 3(6), 599-605.