Autologous Stem Cell Transplantation for T-Cell Lymphomas

Perrone Giulia, Paolo Corradini

Research output: Contribution to journalArticle

Abstract

Peripheral T-cell lymphomas (PTCLs) are a rare and heterogeneous group of T-cell malignancies characterized by a very poor outcome. The optimal treatment for PTCLs remains controversial. The role of stem cell transplantation in PTCLs has been investigated; however, no randomized control studies specifically dedicated to PTCLs are currently available. Several retrospective and prospective studies have suggested that high-dose chemotherapy (HDT) followed by autologous stem cell transplantation (ASCT) may improve the survival in patients with chemosensitive T-cell lymphoma, either upfront or as salvage treatment. This review provides a summary of the current literature with the intent to explore the role of ASCT in various clinical scenarios.

Original languageEnglish
Pages (from-to)59-66
Number of pages8
JournalSeminars in Hematology
Volume51
Issue number1
DOIs
Publication statusPublished - Jan 2014

ASJC Scopus subject areas

  • Hematology

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