AUTOMATED ANALYSIS OF MYOCARDIAL AUTORADIOGRAPHS FOR THE STUDY OF REGIONAL GLUCOSE METABOLISM.

G. Valli, P. Camici, G. Coppino, P. Greco, A. L'Abbate

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Autoradiographs were obtained from 40 mu m slices of dog hearts after i. v. injection of 1 mCi of C14-deoxyglucose (C14-DG). The optical density of the autoradiographs was assumed related to the C14-DG content. The autoradiographs were scanned by a TV camera and real time digitized into a 256 multiplied by 256 8 bit matrix. The boundary between the two ventricles was recognized and the two ventricles analyzed separately. LV and RV were further divided into wedges and layers to obtain 32 areas from each slice. Regional myocardial blood flow was assessed in correspondinag areas of alternate heart slices by the radioactive microsphere technique. A direct relation between regional flow and glucose uptake was found in the heart of the anesthetized open chest dog; however, a higher supply/uptake ratio was observed in RV as compared to LV.

Original languageEnglish
Title of host publicationComputers in Cardiology
PublisherIEEE
Pages305-308
Number of pages4
Publication statusPublished - 1980
EventUnknown conference - Williamsburg, VA, USA
Duration: Oct 22 1980Oct 24 1980

Other

OtherUnknown conference
CityWilliamsburg, VA, USA
Period10/22/8010/24/80

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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