Automatic integration of PET/CT images for clinical use in radiotherapy

G. Rizzo, R. Arienti, I. Castiglioni, M. Cattaneo, P. Castellone, C. Landoni, G. Ceresoli, C. Messa, M. C. Gilardi, S. Cerutti, F. Fazio

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We implemented an automatic method based on maximization of mutual information (MI), suitable for clinical use for registration of CT and PET images in radiotherapy planning. The integration of anatomical CT information with functional PET data allows a better definition of the tumour volume with respect to the conventional CT based approach. The accuracy of spatial realignment obtained with the proposed approach was investigated in experimental data, relative to phantom and patient studies and was found adequate for radiotherapy application. An application of the MI matching method to a patient affected by non-small lung cancer is presented, showing the differences between CT and multimodal PET/CT radiotherapy treatment plans.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
EditorsR.S. Leder
Pages603-606
Number of pages4
Volume1
Publication statusPublished - 2003
EventA New Beginning for Human Health: Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Cancun, Mexico
Duration: Sep 17 2003Sep 21 2003

Other

OtherA New Beginning for Human Health: Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CountryMexico
CityCancun
Period9/17/039/21/03

Keywords

  • Multimodal registration
  • Mutual information
  • PET
  • Radiotherapy

ASJC Scopus subject areas

  • Bioengineering

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  • Cite this

    Rizzo, G., Arienti, R., Castiglioni, I., Cattaneo, M., Castellone, P., Landoni, C., Ceresoli, G., Messa, C., Gilardi, M. C., Cerutti, S., & Fazio, F. (2003). Automatic integration of PET/CT images for clinical use in radiotherapy. In R. S. Leder (Ed.), Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 1, pp. 603-606)