Automation of in-silico data analysis processes through workflow management systems

Research output: Contribution to journalArticle

Abstract

Data integration is needed in order to cope with the huge amounts of biological information now available and to perform data mining effectively. Current data integration systems have strict limitations, mainly due to the number of resources, their size and frequency of updates, their heterogeneity and distribution on the Internet. Integration must therefore be achieved by accessing network services through flexible and extensible data integration and analysis network tools. EXtensible Markup Language (XML), Web Services and Workflow Management Systems (WMS) can support the creation and deployment of such systems. Many XML languages and Web Services for bioinformatics have already been designed and implemented and some WMS have been proposed. In this article, we review a methodology for data integration in biomedical research that is based on these technologies. We also briefly describe some of the available WMS and discuss the current limitations of this methodology and the ways in which they can be overcome.

Original languageEnglish
Pages (from-to)57-68
Number of pages12
JournalBriefings in Bioinformatics
Volume9
Issue number1
DOIs
Publication statusPublished - Jan 2008

Keywords

  • Automation of retrieval and analysis processes
  • Biological data integration
  • Ontologies
  • Web services
  • Workflow management systems
  • XML

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Information Systems
  • Software

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