Autonomic modulation and clinical outcome in patients with chronic heart failure

Antonio Franco Folino, Barbara Tokajuk, Alberto Porta, Silvia Romano, Sergio Cerutti, Sergio Dalla Volta

Research output: Contribution to journalArticlepeer-review


Objective: Several studies documented the relevance of autonomic activity in the pathophysiology of heart failure. In our study we evaluated the adjustment of this activity under different stimuli, by means of heart rate variability (HRV), and correlated these findings with long-term mortality and sustained VT occurrence. Patients and method: Fifty-three patients (mean age 54±9 years) with heart failure were submitted to time and frequency domain HRV analysis. This latter analysis was performed at rest, during paced breathing and during passive tilt. Results: Lower standard deviation of RR intervals (76.76±24 versus 107.70±43, p=0.02), mean of the 5-min standard deviations of RR intervals (35.14±15 versus 62.39, p

Original languageEnglish
Pages (from-to)247-251
Number of pages5
JournalInternational Journal of Cardiology
Issue number2
Publication statusPublished - Apr 20 2005


  • Autonomic nervous system
  • Heart failure
  • Heart rate variability
  • Mortality
  • Ventricular arrhythmias

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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