Recently, we have demonstrated a significant correlation between the fragile X syndrome and a particular EEG pattern, very similar to that of the benign childhood epilepsy with centrotemporal spikes. More than 20% of these patients are affected by epilepsy. These findings induced us to re-examine a group of 721 subjects with mental retardation who were admitted to our institute between 1980 and 1991, in whom a karyotype was performed. Rare autosomal fragile sites were considered: 10q25, 12q24, and 16q22. Also these fragile sites seem to be significantly correlated with epilepsy.
|Translated title of the contribution||Autosomal fragile sites and epilepsy|
|Number of pages||3|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 1992|
ASJC Scopus subject areas
- Clinical Neurology