Abstract
Recently, we have demonstrated a significant correlation between the fragile X syndrome and a particular EEG pattern, very similar to that of the benign childhood epilepsy with centrotemporal spikes. More than 20% of these patients are affected by epilepsy. These findings induced us to re-examine a group of 721 subjects with mental retardation who were admitted to our institute between 1980 and 1991, in whom a karyotype was performed. Rare autosomal fragile sites were considered: 10q25, 12q24, and 16q22. Also these fragile sites seem to be significantly correlated with epilepsy.
Translated title of the contribution | Autosomal fragile sites and epilepsy |
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Original language | Italian |
Pages (from-to) | 43-45 |
Number of pages | 3 |
Journal | Bollettino - Lega Italiana contro l'Epilessia |
Issue number | 79-80 |
Publication status | Published - 1992 |
ASJC Scopus subject areas
- Clinical Neurology