Aversive pavlovian conditioning in psychopaths: Peripheral and central correlates

Herta Flor, Niels Birbaumer, Christiane Hermann, Silvio Ziegler, Christopher J. Patrick

Research output: Contribution to journalArticle

167 Citations (Scopus)

Abstract

Differential aversive Pavlovian conditioning with a foul odor as unconditioned stimulus (US) and neutral faces as conditioned stimuli (CS) was compared between 9 noncriminal psychopaths as defined by the Hare Psychopathy Checklist Revised and 12 healthy controls. Event-related potentials (ERP), heart rate, skin conductance response, corrugator EMG, and startle response potentiation as well as valence, arousal, and contingency of the CS were assessed. Whereas the healthy controls (HC) showed significant CS+/CS- differentiation, the psychopaths (PP) failed to exhibit a conditioned response although unconditioned responses were comparable between the groups. N100, P200, and P300 to the CSs revealed that psychopaths were not deficient in information processing and showed even better anticipatory responding than the HC group indicated by the terminal contingent negative variation (tCNV), that lacked, however, CS+ and CS- differentiation. These data indicate a deficit in association formation in psychopaths that may be related to deficient interaction of limbic-subcortical and cortical structures.

Original languageEnglish
Pages (from-to)505-518
Number of pages14
JournalPsychophysiology
Volume39
Issue number4
DOIs
Publication statusPublished - 2002

Fingerprint

Startle Reflex
Contingent Negative Variation
Hares
Arousal
Checklist
Automatic Data Processing
Evoked Potentials
Heart Rate
Control Groups
Skin
Odorants
Conditioning (Psychology)

Keywords

  • Conditioning
  • Contingent negative variation
  • Electromyogram
  • Heart rate
  • Psychopaths

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)
  • Psychology(all)
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology

Cite this

Flor, H., Birbaumer, N., Hermann, C., Ziegler, S., & Patrick, C. J. (2002). Aversive pavlovian conditioning in psychopaths: Peripheral and central correlates. Psychophysiology, 39(4), 505-518. https://doi.org/10.1017/S0048577202394046

Aversive pavlovian conditioning in psychopaths : Peripheral and central correlates. / Flor, Herta; Birbaumer, Niels; Hermann, Christiane; Ziegler, Silvio; Patrick, Christopher J.

In: Psychophysiology, Vol. 39, No. 4, 2002, p. 505-518.

Research output: Contribution to journalArticle

Flor, H, Birbaumer, N, Hermann, C, Ziegler, S & Patrick, CJ 2002, 'Aversive pavlovian conditioning in psychopaths: Peripheral and central correlates', Psychophysiology, vol. 39, no. 4, pp. 505-518. https://doi.org/10.1017/S0048577202394046
Flor, Herta ; Birbaumer, Niels ; Hermann, Christiane ; Ziegler, Silvio ; Patrick, Christopher J. / Aversive pavlovian conditioning in psychopaths : Peripheral and central correlates. In: Psychophysiology. 2002 ; Vol. 39, No. 4. pp. 505-518.
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