Awake surgery between art and science. Part I: Clinical and operative settings

Andrea Talacchi, Barbara Santini, Francesca Casagrande, Franco Alessandrini, Giada Zoccatelli, Giovanna M. Squintani

Research output: Contribution to journalArticlepeer-review


Awake surgery requires coordinated teamwork and communication between the surgeon and the anesthesiologist, as he monitors the patient, the neuroradiologist as he interprets the images for intraoperative confirmation, and the neuropsychologist and neurophysiologist as they evaluate in real-time the patient's responses to commands and questions. To improve comparison across published studies on clinical assessment and operative settings in awake surgery, we reviewed the literature, focusing on methodological differences and aims. In complex, interdisciplinary medical care, such differences can affect the outcome and the cost-benefit ratio of the treatment. Standardization of intraoperative mapping and related controversies will be discussed in Part II.

Original languageEnglish
Pages (from-to)205-221
Number of pages17
JournalFunctional Neurology
Issue number3
Publication statusPublished - 2013


  • Brain tumors
  • Complications
  • Language assessment
  • Neuropsychological assessment
  • Surgical treatment

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)
  • Medicine(all)


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