Axillary injection of botulinum A toxin in a patient with muscle cramps associated with severe axillary hyperhidrosis

Massimiliano Filosto, Laura Bertolasi, Emiliana Fincati, Alberto Priori, Giuliano Tomelleri, Giancarlo Chieregato, Nicolà Rizzuto

Research output: Contribution to journalArticle

Abstract

Muscle cramps may be caused by fluid and salt loss induced by diffuse or focal hyperhidrosis. Recent reports have described the efficacy of botulinum toxin in the treatment of primary focal hyperhidrosis. Botulinum toxin inhibits sweating by blocking exocytosis of acetylcholine from presynaptic cholinergic nerve terminals. We report the case of a patient who complained of frequent muscle cramps associated with unusually severe axillary hyperhidrosis. We used botulinum toxin to treat the excessive focal sweating presuming that it would also reduce the muscle cramps. A total dose of 200 MU of botulinum A toxin (Dysport) per axilla markedly reduced sweating and cramps. The beneficial effect started four days after the injection and it was still present five months later Treatment was repeated in the sixth month with analogous results. No side-effects were observed and no compensatory sweating occurred.

Original languageEnglish
Pages (from-to)121-123
Number of pages3
JournalActa Neurologica Belgica
Volume101
Issue number2
Publication statusPublished - 2001

Keywords

  • Axillary hyperhidrosis
  • Botulinum toxin
  • Cramps

ASJC Scopus subject areas

  • Clinical Neurology

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    Filosto, M., Bertolasi, L., Fincati, E., Priori, A., Tomelleri, G., Chieregato, G., & Rizzuto, N. (2001). Axillary injection of botulinum A toxin in a patient with muscle cramps associated with severe axillary hyperhidrosis. Acta Neurologica Belgica, 101(2), 121-123.