Abstract
A 44-year-old man developed a peripheral neuropathy during treatment with interferon-α for chronic hepatitis C. The onset was insidious, beginning symmetrically in the hands with paresthesia. Neurophysiological investigation revealed a predominantly sensory axonal neuropathy. A sural nerve biopsy confirmed primary axonal damage. Immunofluorescence studies showed increased expression of HLA-DR molecules prevalently on Schwann cells of non-myelin-forming type.
Original language | English |
---|---|
Pages (from-to) | 504-508 |
Number of pages | 5 |
Journal | Acta Neuropathologica |
Volume | 94 |
Issue number | 5 |
DOIs | |
Publication status | Published - 1997 |
Keywords
- Hepatitis C
- HLA-DR antigens
- Interferon-α
- Neuropathy
ASJC Scopus subject areas
- Clinical Neurology
- Pathology and Forensic Medicine
- Neuroscience(all)