B and T lymphocyte subsets in fetal and cord blood: Age-Related modulation of CD1c expression

A. Plebani, A. R. Proserpio, D. Guarneri, M. Buscaglia, G. Cattoretti

Research output: Contribution to journalArticle

Abstract

Peripheral blood lymphocytes from fetal, term and adult subjects were analyzed with a panel of B- and T-lymphoid differentiation markers. CD1c +ve and CD5 +ve B cell (IgM +ve) percentage in fetal, cord and adult blood decreased significantly. Fetal and cord blood contained less CD2+ and CD3+ T Iymphocytes and a higher percentage of CD38 +ve cells than adult blood. The phenotypic changes occurring during perinatal age in humans relate to the changes in the functional activities of the B and T lymphoid subsets from fetal to postnatal age.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalBiology of the Neonate
Volume63
Issue number1
Publication statusPublished - 1993

Keywords

  • Cd1c
  • Fetal blood
  • Lymphocytes
  • Ontogeny

ASJC Scopus subject areas

  • Developmental Biology
  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'B and T lymphocyte subsets in fetal and cord blood: Age-Related modulation of CD1c expression'. Together they form a unique fingerprint.

  • Cite this

    Plebani, A., Proserpio, A. R., Guarneri, D., Buscaglia, M., & Cattoretti, G. (1993). B and T lymphocyte subsets in fetal and cord blood: Age-Related modulation of CD1c expression. Biology of the Neonate, 63(1), 1-7.