Peripheral blood lymphocytes from fetal, term and adult subjects were analyzed with a panel of B- and T-lymphoid differentiation markers. CD1c +ve and CD5 +ve B cell (IgM +ve) percentage in fetal, cord and adult blood decreased significantly. Fetal and cord blood contained less CD2+ and CD3+ T Iymphocytes and a higher percentage of CD38 +ve cells than adult blood. The phenotypic changes occurring during perinatal age in humans relate to the changes in the functional activities of the B and T lymphoid subsets from fetal to postnatal age.
|Number of pages||7|
|Journal||Biology of the Neonate|
|Publication status||Published - 1993|
- Fetal blood
ASJC Scopus subject areas
- Developmental Biology
- Pediatrics, Perinatology, and Child Health