B lymphocyte subsets and their functional activity in the early months of life

M. A. Avanzini; R. Maccario; C. Belloni; G. Carrera; A. Bertaina; M. Cagliuso; M. La Rocca; C. Valsecchi; M. Mantelli; A. M. Castellazzi; I. Quinti; A. De Silvestri; M. Marconi

B lymphocyte subsets and their functional activity in the early months of life

M. A. Avanzini, R. Maccario, C. Belloni, G. Carrera, A. Bertaina, M. Cagliuso, M. La Rocca, C. Valsecchi, M. Mantelli, A. M. Castellazzi, I. Quinti, A. De Silvestri, M. Marconi

Research output: Contribution to journal › Article › peer-review

Abstract

In the present study we evaluated B-cell subsets and their functional development in 74 newborns from birth to 6 months of life. Moreover, we evaluated "natural antibody" production in vitro. The results documented a predominance of naive B-lymphocytes at all time-points evaluated, decreasing from birth to 6 months (p=0.009). The percentages of CD27 ⁺IgD⁺ and CD27⁺I gD^neg memory B-cells were very low at birth and significantly increased only at 6 months (p=0.02 and p

Original language	English
Pages (from-to)	247-254
Number of pages	8
Journal	International Journal of Immunopathology and Pharmacology
Volume	23
Issue number	1
Publication status	Published - Jan 2010

Keywords

B lymphocytes
Ig production
Natural antibodies
Neonate

ASJC Scopus subject areas

Pharmacology
Immunology
Immunology and Allergy

Fingerprint Dive into the research topics of 'B lymphocyte subsets and their functional activity in the early months of life'. Together they form a unique fingerprint.

Cite this

B lymphocyte subsets and their functional activity in the early months of life. / Avanzini, M. A.; Maccario, R.; Belloni, C.; Carrera, G.; Bertaina, A.; Cagliuso, M.; La Rocca, M.; Valsecchi, C.; Mantelli, M.; Castellazzi, A. M.; Quinti, I.; De Silvestri, A.; Marconi, M.

In: International Journal of Immunopathology and Pharmacology, Vol. 23, No. 1, 01.2010, p. 247-254.

Research output: Contribution to journal › Article › peer-review

Avanzini, M. A. ; Maccario, R. ; Belloni, C. ; Carrera, G. ; Bertaina, A. ; Cagliuso, M. ; La Rocca, M. ; Valsecchi, C. ; Mantelli, M. ; Castellazzi, A. M. ; Quinti, I. ; De Silvestri, A. ; Marconi, M. / B lymphocyte subsets and their functional activity in the early months of life. In: International Journal of Immunopathology and Pharmacology. 2010 ; Vol. 23, No. 1. pp. 247-254.

@article{cd5eac670cd14615a7aa0eb7958c9bfb,

title = "B lymphocyte subsets and their functional activity in the early months of life",

abstract = "In the present study we evaluated B-cell subsets and their functional development in 74 newborns from birth to 6 months of life. Moreover, we evaluated {"}natural antibody{"} production in vitro. The results documented a predominance of naive B-lymphocytes at all time-points evaluated, decreasing from birth to 6 months (p=0.009). The percentages of CD27 +IgD+ and CD27+I gDneg memory B-cells were very low at birth and significantly increased only at 6 months (p=0.02 and p",

keywords = "B lymphocytes, Ig production, Natural antibodies, Neonate",

author = "Avanzini, {M. A.} and R. Maccario and C. Belloni and G. Carrera and A. Bertaina and M. Cagliuso and {La Rocca}, M. and C. Valsecchi and M. Mantelli and Castellazzi, {A. M.} and I. Quinti and {De Silvestri}, A. and M. Marconi",

year = "2010",

month = jan,

language = "English",

volume = "23",

pages = "247--254",

journal = "International Journal of Immunopathology and Pharmacology",

issn = "0394-6320",

publisher = "Biomedical Research Press s.a.s.",

number = "1",

}

TY - JOUR

T1 - B lymphocyte subsets and their functional activity in the early months of life

AU - Avanzini, M. A.

AU - Maccario, R.

AU - Belloni, C.

AU - Carrera, G.

AU - Bertaina, A.

AU - Cagliuso, M.

AU - La Rocca, M.

AU - Valsecchi, C.

AU - Mantelli, M.

AU - Castellazzi, A. M.

AU - Quinti, I.

AU - De Silvestri, A.

AU - Marconi, M.

PY - 2010/1

Y1 - 2010/1

N2 - In the present study we evaluated B-cell subsets and their functional development in 74 newborns from birth to 6 months of life. Moreover, we evaluated "natural antibody" production in vitro. The results documented a predominance of naive B-lymphocytes at all time-points evaluated, decreasing from birth to 6 months (p=0.009). The percentages of CD27 +IgD+ and CD27+I gDneg memory B-cells were very low at birth and significantly increased only at 6 months (p=0.02 and p

AB - In the present study we evaluated B-cell subsets and their functional development in 74 newborns from birth to 6 months of life. Moreover, we evaluated "natural antibody" production in vitro. The results documented a predominance of naive B-lymphocytes at all time-points evaluated, decreasing from birth to 6 months (p=0.009). The percentages of CD27 +IgD+ and CD27+I gDneg memory B-cells were very low at birth and significantly increased only at 6 months (p=0.02 and p

KW - B lymphocytes

KW - Ig production

KW - Natural antibodies

KW - Neonate

UR - http://www.scopus.com/inward/record.url?scp=77951741939&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951741939&partnerID=8YFLogxK

M3 - Article

C2 - 20378010

AN - SCOPUS:77951741939

VL - 23

SP - 247

EP - 254

JO - International Journal of Immunopathology and Pharmacology

JF - International Journal of Immunopathology and Pharmacology

SN - 0394-6320

IS - 1

ER -

B lymphocyte subsets and their functional activity in the early months of life

Abstract

Keywords

ASJC Scopus subject areas

Other files and links

Cite this