Background neuronal activity in cat somatosensory cortex before and after VPL damage. Histogram and taxonomic analysis

S. Moyanova, E. Atsev, V. I. Maloletnev

Research output: Contribution to journalArticle

Abstract

Two groups of cats under barbiturate anaesthesia were used to study the effect of electrolytic coagulation in the VPL of the thalamus on extracellular unit activity in the somatosensory cortex (the focus of maximal activity (FMA) of this part of the nucleus affected by the lesion). In the first group of animals a comparison is made between the unit activity before and immediately after coagulation, while in the second group of animals the activity of the neurones, recorded in FMA of the intact VPL is compared with that of the neurones in the homologous symmetrical point in the hemisphere, ipsilateral to the VPL coagulate, 10-14 days before the acute experiment. The activity of 245 neurons was studied. Histogram, statistical and taxonomic analyses were performed. It was found that a lesion in the VPL modifies to a certain extent the pattern of neuronal discharges, although even after the damage rhythmic groups of action potentials simultaneous with the spindle-like EEG waves are recorded in the primary somatosensory cortex (FMA). Evidently, the relay VPL nucleus is not the only pacemaker of spindle activity in its projection cortical area, which is contradicts some views expressed in the literature.

Original languageEnglish
Pages (from-to)43-50
Number of pages8
JournalActa Physiologica et Pharmacologica Bulgarica
Volume4
Issue number4
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Physiology
  • Pharmacology

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